2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine

Base Information

Chemical Name:2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine
CAS No.:85278-66-6
Molecular Formula:C11H14FNO2
Molecular Weight:211.2328
Hs Code.:2922299090
Nikkaji Number:J367.363D
Wikidata:Q76386640
ChEMBL ID:CHEMBL445285
Mol file:85278-66-6.mol

Synonyms:2-(3,4-dimethoxyphenyl)-3-fluoroallylamine;2-DLPFA;MDL 72145;MDL-72145

Suppliers and Price of 2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(3,4-DIMETHOXYPHENYL)-3-FLUOROALLYLAMINE 95.00%
5MG
$ 498.41

Total 1 raw suppliers

Chemical Property of 2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine

Chemical Property:

Vapor Pressure:9.76E-05mmHg at 25°C
Boiling Point:338.5°Cat760mmHg
Flash Point:158.5°C
PSA：44.48000
Density:1.106g/cm³
LogP:2.67320
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:211.10085685
Heavy Atom Count:15
Complexity:221

Purity/Quality:

99%+ ^*data from raw suppliers

2-(3,4-DIMETHOXYPHENYL)-3-FLUOROALLYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(=CF)CN)OC
Isomeric SMILES:COC1=C(C=C(C=C1)/C(=C\F)/CN)OC

Technology Process of 2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine

There total 9 articles about 2-(3,4-Dimethoxyphenyl)-3-fluoroallylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85277-95-8
(E)-1-fluoro-2-(3,4-dimethoxyphenyl)-3-phthalimidopropene

: 85278-66-6
(E)-2-(3',4'-dimethoxyphenyl)-3-fluoroallylamine

Guidance literature:: With hydrazine;
DOI:10.1021/jm00367a002

Reference yield:

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 85278-66-6
(E)-2-(3',4'-dimethoxyphenyl)-3-fluoroallylamine

Guidance literature:: Multi-step reaction with 9 steps

1: HClO₄

2: LDA

3: t-BuONa

4: CF₃CO₂H

5: NaOH

6: diisobutylaluminium hydride (DIBAL) / hexane

7: PBr₃

9: NH₂NH₂

With sodium hydroxide; perchloric acid; phosphorus tribromide; diisobutylaluminium hydride; trifluoroacetic acid; sodium t-butanolate; hydrazine; lithium diisopropyl amide; In hexane;
DOI:10.1021/jm00367a002

Reference yield:

: 13790-42-6
tert-butyl 3,4-dimethoxyphenylacetate

: 85278-66-6
(E)-2-(3',4'-dimethoxyphenyl)-3-fluoroallylamine

Guidance literature:: Multi-step reaction with 8 steps

1: LDA

2: t-BuONa

3: CF₃CO₂H

4: NaOH

5: diisobutylaluminium hydride (DIBAL) / hexane

6: PBr₃

8: NH₂NH₂

With sodium hydroxide; phosphorus tribromide; diisobutylaluminium hydride; trifluoroacetic acid; sodium t-butanolate; hydrazine; lithium diisopropyl amide; In hexane;
DOI:10.1021/jm00367a002