2-[3,4-Dihydro-8-methyl-8-(4-methyl-3-pentenyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-5-methoxyphenol

Base Information

• Chemical Name: 2-[3,4-Dihydro-8-methyl-8-(4-methyl-3-pentenyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-5-methoxyphenol
• CAS No.: 66446-90-0
• Molecular Formula: C₂₆H₃₀O₄
• Molecular Weight: 406.522
• Mol file: 66446-90-0.mol

Synonyms:5-Methoxy-2-[8-methyl-8-(4-methyl-pent-3-enyl)-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-phenol;

Chemical Property of 2-[3,4-Dihydro-8-methyl-8-(4-methyl-3-pentenyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-5-methoxyphenol

Chemical Property:

• Melting Point: 80 °C
• PSA: 47.92000
• LogP: 6.03020

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[3,4-Dihydro-8-methyl-8-(4-methyl-3-pentenyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-5-methoxyphenol

There total 7 articles about 2-[3,4-Dihydro-8-methyl-8-(4-methyl-3-pentenyl)-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-5-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-benzyloxy-7-hydroxy-4'-methoxyisoflavone (67052-49-7) → (+/-)-heminitidulan (66446-90-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 61 percent / NaOH, Adogen 464 / H₂O; CH₂Cl₂ / Ambient temperature

2: 62 percent / H₂ / 10percent Pd-C / ethanol; acetic acid / 6 h / 2280 Torr / Ambient temperature

3: 50 percent / K₂CO₃ / acetone / 2 h / 60 °C / Heating

4: 89 percent / 3N HCl / methanol / 1 h / Heating

5: 11 percent / pyridine / 12 h / 200 °C

6: 10 mg / zinc powder / acetic acid / 1 h / steam bath

With hydrogenchloride; sodium hydroxide; adogen 464; hydrogen; potassium carbonate; zinc; palladium on activated charcoal; In pyridine; methanol; ethanol; dichloromethane; water; acetic acid; acetone;

Reference yield:

2'-benzyloxy-4'-methoxy-7-(methoxymethoxy)isoflavone (76436-55-0) → (+/-)-heminitidulan (66446-90-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 62 percent / H₂ / 10percent Pd-C / ethanol; acetic acid / 6 h / 2280 Torr / Ambient temperature

2: 50 percent / K₂CO₃ / acetone / 2 h / 60 °C / Heating

3: 89 percent / 3N HCl / methanol / 1 h / Heating

4: 11 percent / pyridine / 12 h / 200 °C

5: 10 mg / zinc powder / acetic acid / 1 h / steam bath

With hydrogenchloride; hydrogen; potassium carbonate; zinc; palladium on activated charcoal; In pyridine; methanol; ethanol; acetic acid; acetone;

Reference yield:

2'-O-phenacylheminitidulan (76436-60-7) → (+/-)-heminitidulan (66446-90-0)

Guidance literature:

With zinc; In acetic acid; for 1h; steam bath;

upstream raw materials:

2'-O-phenacylheminitidulan

2'-benzyloxy-7-hydroxy-4'-methoxyisoflavone

7-hydroxy-4'-methoxy-2'-phenacyloxyisoflavan

2'-benzyloxy-4'-methoxy-7-(methoxymethoxy)isoflavone