N-Hydroxysulfosuccinimide

Base Information

• Chemical Name: N-Hydroxysulfosuccinimide
• CAS No.: 82436-78-0
• Molecular Formula: C4H5 N O6 S
• Molecular Weight: 195.15
• Hs Code.: 2925190090
• Mol file: 82436-78-0.mol

Synonyms:3-Sulfo-N-hydroxysuccinimide;N-Hydroxysulfosuccinimide; Sulfo-N-hydroxysuccinimide; Sulfo-NHS

Chemical Property of N-Hydroxysulfosuccinimide

Chemical Property:

• PSA: 120.36000
• LogP: -0.59040
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-Hydroxysulphosuccinimide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Hydroxysulfosuccinimide

There total 1 articles about N-Hydroxysulfosuccinimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-hydroxy-2,5-dioxopyrrolidine-3-sulfonic acid (82436-78-0)

Guidance literature:

Reference yield: 71.0%

N-hydroxy-2,5-dioxopyrrolidine-3-sulfonic acid (82436-78-0) + benzoic acid (65-85-0,8013-63-6) → C11H9NO7S

Guidance literature:

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 24h;

DOI:10.1016/j.carres.2007.05.029

Reference yield: 19.0%

C30H23F12N2O4(1+) + N-hydroxy-2,5-dioxopyrrolidine-3-sulfonic acid (82436-78-0) → C34H25F12N3O9S

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃; for 20h;

DOI:10.1039/c7cc07783a

Downstream raw materials:

N-sulfosuccinimidyl-(4-iodoacetyl)-aminobenzoate

ε-(p-azidobenzene-sulfonyl)aminocaproic acid (N-hydroxysuccinimide-2-sulfonic acid) ester

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