Phenol, 3-(3-phenoxyphenoxy)-

Base Information

• Chemical Name: Phenol, 3-(3-phenoxyphenoxy)-
• CAS No.: 14200-84-1
• Molecular Formula: C18H14 O3
• Molecular Weight: 278.307
• Hs Code.: 2909500000
• NSC Number: 87876
• DSSTox Substance ID: DTXSID5065726
• Nikkaji Number: J421.912K
• Wikidata: Q81992353
• Mol file: 14200-84-1.mol

Synonyms:3-(3-phenoxyphenoxy)phenol;Phenol, 3-(3-phenoxyphenoxy)-;m-(m-Phenoxyphenoxy)phenol;14200-84-1;Phenol, m-(m-phenoxyphenoxy)-;NSC 87876;3-[3-(phenoxy)phenoxy]phenol;NSC87876;Oprea1_560233;SCHEMBL1174127;DTXSID5065726;NSC-87876;SR-01000390190;SR-01000390190-1

Chemical Property of Phenol, 3-(3-phenoxyphenoxy)-

Chemical Property:

• Vapor Pressure: 6.88E-08mmHg at 25°C
• Boiling Point: 426.9°Cat760mmHg
• Flash Point: 212°C
• PSA: 38.69000
• Density: 1.215g/cm³
• LogP: 4.97680
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 278.094294304
• Heavy Atom Count: 21
• Complexity: 301

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=CC(=CC=C2)OC3=CC=CC(=C3)O

Technology Process of Phenol, 3-(3-phenoxyphenoxy)-

There total 4 articles about Phenol, 3-(3-phenoxyphenoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4′,6′-bis([1,1′-biphenyl]-4-yloxy)-5′-bromo-1,1′:3′,1″-terphenyl (23840-43-9) → m-(m-phenoxyphenoxy)phenol (14200-84-1)

Guidance literature:

With potassium hydroxide; In diethylene glycol; at 230 - 240 ℃;

DOI:10.1021/jo01079a029

Reference yield:

meta-phenoxyphenol (713-68-8) → m-(m-phenoxyphenoxy)phenol (14200-84-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) aq. KOH, (ii) /BRN= 1904538/, Cu, (heating)

2: aq. KOH / bis-(2-hydroxy-ethyl) ether / 230 - 240 °C

With potassium hydroxide; In diethylene glycol;

DOI:10.1021/jo01079a029

Reference yield:

1-methoxy-3-phenoxybenzene (1655-68-1) → m-(m-phenoxyphenoxy)phenol (14200-84-1)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. HBr, AcOH, Ac₂O

2: (i) aq. KOH, (ii) /BRN= 1904538/, Cu, (heating)

3: aq. KOH / bis-(2-hydroxy-ethyl) ether / 230 - 240 °C

With potassium hydroxide; hydrogen bromide; acetic anhydride; acetic acid; In diethylene glycol;

DOI:10.1021/jo01079a029

upstream raw materials:

4′,6′-bis([1,1′-biphenyl]-4-yloxy)-5′-bromo-1,1′:3′,1″-terphenyl

meta-phenoxyphenol

1-methoxy-3-phenoxybenzene

Downstream raw materials:

1,3-bis[3-(3-phenoxyphenoxy)phenoxy]benzene

1,1'-oxybis[m-(m-phenoxyphenoxy)benzene]

Methyl (m-[m-phenoxyphenoxy]phenoxy)-α-[p-(p-chlorophenoxy)phenyl]acetate