(S)-4-(4-Methoxyphenyl)butan-2-amine

Base Information

Chemical Name:(S)-4-(4-Methoxyphenyl)butan-2-amine
CAS No.:66264-86-6
Molecular Formula:C11H17NO
Molecular Weight:179.262
Hs Code.:2922299090
European Community (EC) Number:266-290-8
DSSTox Substance ID:DTXSID101270574
Nikkaji Number:J2.997.064E

Synonyms:66264-86-6;(S)-4-(4-Methoxyphenyl)butan-2-amine;(2S)-4-(4-methoxyphenyl)butan-2-amine;(S)-1-Methyl-3-(4-methoxy-phenyl)-propylamine;(S)-1-METHYL-3-(P-METHOXYPHENYL)PROPYLAMINE;SCHEMBL8975067;DTXSID101270574;MFCD00671662;(S)-4-(4-Methoxyphenyl)butane-2-amine;Benzenepropanamine,4-methoxy-a-methyl-,(as)-;EN300-1842493;(alphaS)-4-Methoxy-alpha-methylbenzenepropanamine;BENZENEPROPANAMINE,4-METHOXY-A-METHYL-, (AS)-

Suppliers and Price of (S)-4-(4-Methoxyphenyl)butan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2S)-4-(4-METHOXYPHENYL)BUTAN-2-AMINE 95.00%
5MG
$ 505.79

Total 8 raw suppliers

Chemical Property of (S)-4-(4-Methoxyphenyl)butan-2-amine

Chemical Property:

Vapor Pressure:0.00474mmHg at 25°C
Refractive Index:1.514
Boiling Point:276.6 °C at 760 mmHg
Flash Point:116.4 °C
PSA：35.25000
Density:0.977 g/cm³
LogP:2.67530
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:179.131014166
Heavy Atom Count:13
Complexity:130

Purity/Quality:

98% ^*data from raw suppliers

(2S)-4-(4-METHOXYPHENYL)BUTAN-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC1=CC=C(C=C1)OC)N
Isomeric SMILES:C[C@@H](CCC1=CC=C(C=C1)OC)N

Technology Process of (S)-4-(4-Methoxyphenyl)butan-2-amine

There total 5 articles about (S)-4-(4-Methoxyphenyl)butan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 690244-74-7
1-((S)-3-Azido-butyl)-4-methoxy-benzene

: 66264-86-6
(-)-(S)-3-(4-methoxyphenyl)-1-methylpropylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃;
DOI:10.1016/j.bmcl.2004.01.040

Reference yield:

: N-(4-(4-methoxyphenyl)butan-2-yl)pyridin-2-amine

: 66264-86-6
(-)-(S)-3-(4-methoxyphenyl)-1-methylpropylamine

: 66264-83-3
4-(4-methoxyphenyl)butan-2-amine

Guidance literature:: N-(4-(4-methoxyphenyl)butan-2-yl)pyridin-2-amine; With hydrogenchloride; In diethyl ether; dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

With platinum(IV) oxide; hydrogen; In ethanol; at 0 ℃; for 9h; under 760.051 Torr; Inert atmosphere;

With hydrazine; at 75 ℃; for 0.0833333h; optical yield given as %ee; Inert atmosphere;
DOI:10.1021/ol201907w

Reference yield:

: 59092-94-3
(+)-rhododendrol

: 66264-86-6
(-)-(S)-3-(4-methoxyphenyl)-1-methylpropylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / aq. HBr / 6 h / 80 °C

2: 85 percent / K₂CO₃ / acetone / 4 h / Heating

3: 80 percent / NaN₃ / dimethylformamide / 6 h / 70 °C

4: 80 percent / H₂ / Pd/C / ethanol / 20 °C

With sodium azide; hydrogen bromide; hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.bmcl.2004.01.040