4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one

Base Information

Chemical Name:4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one
CAS No.:110254-64-3
Molecular Formula:C15H9 Cl N2 O3
Molecular Weight:300.6966
Hs Code.:
DSSTox Substance ID:DTXSID50353134
Nikkaji Number:J466.309H
Wikidata:Q82130585
Mol file:110254-64-3.mol

Synonyms:4-chloro-3-nitro-1-phenylquinolin-2-one;4-chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one;110254-64-3;4-CHLORO-1-PHENYL-3-NITRO-2(1H)-QUINOLONE;4-chloro-3-nitro-1-phenylquinolin-2(1H)-one;4-chloro-3-nitro-1-phenyl-2(1H)-quinolinone;CBMicro_001184;Cambridge id 5960127;Oprea1_040234;Oprea1_254356;DTXSID50353134;SMSF0010685;STK110609;AKOS001334242;CB02871;BIM-0001250.P001;CS-0270141;4-Chlor-3-nitro- 1-phenyl- 2(1H)-chinolon;4-Chloro-1-phenyl-3-nitroquinolin-2(1H)-one;Z57475613

Suppliers and Price of 4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one

Chemical Property:

Vapor Pressure:2.69E-07mmHg at 25°C
Boiling Point:421°Cat760mmHg
Flash Point:208.4°C
PSA：67.82000
Density:1.5g/cm³
LogP:4.07550
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:300.0301698
Heavy Atom Count:21
Complexity:480

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C3=CC=CC=C3C(=C(C2=O)[N+](=O)[O-])Cl

Technology Process of 4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one

There total 6 articles about 4-Chloro-3-nitro-1-phenyl-1,2-dihydroquinolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 54675-12-6
4-hydroxy-3-nitro-1-phenyl-2(1H)-quinolone

: 110254-64-3
4-chloro-3-nitro-1-phenyl-2(1H)-quinolone

Guidance literature:: With triethylamine; trichlorophosphate; for 1h; Heating;

Reference yield:

: 20877-86-5
N-phenyl isatoic anhydride

: 110254-64-3
4-chloro-3-nitro-1-phenyl-2(1H)-quinolone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) dimethylacetamide, 2.) dimethylacetamide, 170 deg C, 2 h

2: POCl₃ / 0.5 h / Heating

With sodium hydride; trichlorophosphate;
DOI:10.1021/jm00104a013

Reference yield:

: 14994-75-3
4-hydroxy-1-phenylquinolin-2(1H)-one

: 110254-64-3
4-chloro-3-nitro-1-phenyl-2(1H)-quinolone

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / conc. HNO₃, NaNO₂ / acetic acid / 0.5 h

2: 96 percent / triethylamine, phosphoryl chloride / 1 h / Heating

With nitric acid; triethylamine; sodium nitrite; trichlorophosphate; In acetic acid;