glaucasterol

Base Information

Chemical Name:glaucasterol
CAS No.:84871-06-7
Molecular Formula:C₂₇H₄₂O
Molecular Weight:382.63
Hs Code.:
Mol file:84871-06-7.mol

Synonyms:glaucasterol;(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(E)-(R)-1-methyl-3-((1S,2S)-2-methyl-cyclopropyl)-allyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol;

Suppliers and Price of glaucasterol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of glaucasterol

Chemical Property:

PSA：20.23000
LogP:6.77460

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of glaucasterol

There total 22 articles about glaucasterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 115487-75-7
(E)-(1S,2S)-2(methoxy-6β-cyclo-3α,5α) 20S pregnanyl-2-vinyl-1-methylcyclopropane

: 84871-06-7
glaucasterol

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; water; at 90 ℃; for 2h;
DOI:10.1016/S0040-4020(01)87708-5

Reference yield: 50.0%

: 115487-75-7
(1aR,3aR,3bS,5aR,6R,8aS,8bS,10R)-10-Methoxy-3a,5a-dimethyl-6-[(E)-(R)-1-methyl-3-((1S,2S)-2-methyl-cyclopropyl)-allyl]-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalene

: 84871-06-7
glaucasterol

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; water;
DOI:10.1016/S0040-4039(01)90046-2

Reference yield:

: 115487-62-2,115487-63-3
Carbonic acid ethyl ester (Z)-(4R,5S)-4-hydroxy-5-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-hex-2-enyl ester

: 84871-06-7
glaucasterol

Guidance literature:: Multi-step reaction with 8 steps

1: 76 percent / Pd(dppe)2 / tetrahydrofuran / 1 h / 25 °C

2: 89 percent / pyridine; CH₂Cl₂ / 1 h / 25 °C

3: DBU / Pd(dppe)2 / tetrahydrofuran / 0.17 h / Ambient temperature

4: Na₂HPO₄, Na(Hg) / methanol; benzene / 1.) methanol, 2 h room temp.; 2.) benzene, 6 h reflux

5: LiAlH₄ / diethyl ether / 0.17 h / Ambient temperature

6: triethylamine / CH₂Cl₂ / 0.33 h / 0 °C

7: LiAlH₄ / tetrahydrofuran / 0.67 h / 40 °C

8: 87 percent / PTSA / dioxane; H₂O / 2 h / 90 °C

With disodium hydrogenphosphate; lithium aluminium tetrahydride; sodium amalgam; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; bis[1,2-bis(diphenylphosphino)ethane]palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; pyridine; methanol; diethyl ether; dichloromethane; water; benzene;
DOI:10.1016/S0040-4020(01)87708-5