GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Base Information

• Chemical Name: GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
• CAS No.: 107444-51-9
• Molecular Formula: C149H226N40O45
• Molecular Weight: 3297.67
• Mol file: 107444-51-9.mol

Synonyms:Glucagon-relatedpeptide 1 (Rana catesbeiana), 3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine-;(7-36)Glucagon-like peptide-1 amide;(7-36)Glucagon-like peptide-1 amide(human);7-36-Humanglucagon-like peptide I amide;774: PN: WO2004074315 SEQID: 775 claimedprotein;Glucagon-like peptide-I(7-36) amide;Human GLP-1-(7-36)-amide;Humanglucagon-like peptide-1-(7-36) amide;Insulinotropin;Insulinotropin (human);Glp-I (7-36);

Chemical Property of GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Chemical Property:

• Appearance/Colour: White powder
• PSA: 1385.09000
• Density: 1.47 g/cm³
• LogP: 2.02870
• Storage Temp.: −20°C
• Water Solubility.: Soluble in water (1 mg/ml).

Purity/Quality:

99% ^*data from raw suppliers

Glucagon-LikePeptide1(7-36)Amide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Diabetes?II?-?not?yet?an?approved?application Glucagon-Like Peptide-1 is used as a Effector in the hormonal control of insulin secretion. The peptide fragment is secreted from the lower small intestine. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Glucagon-Like Peptide (GLP) I Amide Fragment 7-36 human has been used as a GLP-1 receptor agonist: in lysate transfer cyclic adenosine monophosphate (cAMP) assay to test its effect on adenylyl cyclase activityto pre-treat the human umbilical vein endothelial cells (HUVECs) to monitor its effect on hyperpermeability in endothelial cell (EC) monolayers and changes with the actin cytoskeletonto test its inhibitory effect on vascular endothelial growth factor-A (VEGFA) based vasodilation in rat mesenteric arteries