6-Chloronicotinoyl chloride

Base Information

Chemical Name:6-Chloronicotinoyl chloride
CAS No.:58757-38-3
Molecular Formula:C6H3Cl2NO
Molecular Weight:245.108
Hs Code.:2933399090
European Community (EC) Number:611-746-7,629-450-1
DSSTox Substance ID:DTXSID00974277
Nikkaji Number:J1.124.259F
Wikidata:Q72455636
Mol file:58757-38-3.mol

Synonyms:6-Chloronicotinoyl chloride;58757-38-3;6-Chloropyridine-3-carbonyl Chloride;6-chloronicotinoylchloride;3-Pyridinecarbonyl chloride, 6-chloro-;2-Chloropyridine-5-carbonyl chloride;6-Chloro-nicotinoyl chloride;6-chloronicotinic chloride;6-chloro-nicotinic chloride;SCHEMBL17801;6-Chloronicotinic acid chloride;6-chloro-nicotinic acid chloride;FMEBIWNKYZUWFV-UHFFFAOYSA-;DTXSID00974277;6-Chloronicotinoyl chloride, 97%;6-Chloropyrid-3-ylcarbonyl chloride;6-chloro-3-pyridinecarbonyl chloride;BBL103151;MFCD00051775;STL556961;6-chloro-pyridine-3-carbonyl chloride;AKOS005216119;2G-399S;2-chloropyridine-5-carboxylic acid chloride;AM20061351;C1726;FT-0621084;D78310;EN300-201112;5-Methyl-1,3,4-oxadiazole-2-carboxylicacidpotassiumsalt;Z1255461313;InChI=1/C6H3Cl2NO/c7-5-2-1-4(3-9-5)6(8)10/h1-3H

Suppliers and Price of 6-Chloronicotinoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloronicotinoyl chloride
25g
$ 75.00

TCI Chemical
6-Chloronicotinoyl Chloride >98.0%(T)
5g
$ 29.00

TCI Chemical
6-Chloronicotinoyl Chloride >98.0%(T)
25g
$ 85.00

SynQuest Laboratories
6-Chloronicotinoyl chloride
100 g
$ 416.00

SynQuest Laboratories
6-Chloronicotinoyl chloride
25 g
$ 128.00

Sigma-Aldrich
6-Chloronicotinoyl chloride 97%
25 g
$ 122.00

Matrix Scientific
6-Chloronicotinoyl chloride 97%
1g
$ 56.00

Matrix Scientific
6-Chloronicotinoyl chloride 97%
50g
$ 292.00

Matrix Scientific
6-Chloronicotinoyl chloride 97%
10g
$ 110.00

Biosynth Carbosynth
6-Chloronicotinoyl chloride
25 g
$ 157.50

Total 67 raw suppliers

Chemical Property of 6-Chloronicotinoyl chloride

Chemical Property:

Vapor Pressure:0.0274mmHg at 25°C
Melting Point:48-51 °C(lit.)
Refractive Index:1.566
Boiling Point:246.2 °C at 760 mmHg
PKA:-2.65±0.10(Predicted)
Flash Point:102.7 °C
PSA：29.96000
Density:1.454 g/cm³
LogP:2.11400
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Moisture Sensitive
Solubility.:soluble in Toluene
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:174.9591691
Heavy Atom Count:10
Complexity:140

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloronicotinoyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:Xi,C
Statements: 36/37/38-34
Safety Statements: 26-36-45-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC=C1C(=O)Cl)Cl

Technology Process of 6-Chloronicotinoyl chloride

There total 12 articles about 6-Chloronicotinoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 58757-38-3
6-Chloronicotinoyl chloride

Guidance literature:: With thionyl chloride; at 90 ℃; Inert atmosphere;
DOI:10.1021/op100104z

Reference yield: 86.0%

: 5006-66-6
6-hydroxy-3-pyridinecarboxylic acid

: 58757-38-3
6-Chloronicotinoyl chloride

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide;

Reference yield: 69.0%

: 66572-55-2
6-methoxynicotinic acid

: 58757-38-3
6-Chloronicotinoyl chloride

Guidance literature:: 6-methoxynicotinic acid; With thionyl chloride; for 2h; Reflux;

With N,N-dimethyl-formamide; for 3.5h; Reflux;
DOI:10.1007/s10600-009-9265-6