Quinoline, 4-(p-chlorostyryl)-

Base Information

Chemical Name:Quinoline, 4-(p-chlorostyryl)-
CAS No.:4594-89-2
Molecular Formula:C17H12ClN
Molecular Weight:265.7369
Hs Code.:
NSC Number:204969
Nikkaji Number:J146.098F
ChEMBL ID:CHEMBL1906207
Mol file:4594-89-2.mol

Synonyms:Quinoline, 4-(p-chlorostyryl)-;4-[(E)-2-(4-Chlorophenyl)ethenyl]quinoline;4594-89-2;4-(4-Chlorostyryl)quinoline;NSC204969;CHEMBL1906207;NBYCISZVEKEUFD-VMPITWQZSA-N;trans-4-(4-chlorostyryl)quinoline;AKOS001123702;NSC-204969;NCGC00184246-01;NCGC00184246-02;NCGC00184246-03;NCGC00184246-04;4-[(E)-2-(4-Chlorophenyl)ethenyl]quinoline #;Z94601776

Suppliers and Price of Quinoline, 4-(p-chlorostyryl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Quinoline, 4-(p-chlorostyryl)-

Chemical Property:

Vapor Pressure:3.39E-07mmHg at 25°C
Boiling Point:429.9°Cat760mmHg
Flash Point:246.4°C
PSA：12.89000
Density:1.253g/cm³
LogP:5.05860
XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:265.0658271
Heavy Atom Count:19
Complexity:306

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC=N2)C=CC3=CC=C(C=C3)Cl
Isomeric SMILES:C1=CC=C2C(=C1)C(=CC=N2)/C=C/C3=CC=C(C=C3)Cl

Technology Process of Quinoline, 4-(p-chlorostyryl)-

There total 4 articles about Quinoline, 4-(p-chlorostyryl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 491-35-0
C₆H₄NCH₂CHCCH₂

: 104-88-1
4-chlorobenzaldehyde

: 4594-89-2
C₁₇H₁₂ClN

Guidance literature:: With toluene-4-sulfonamide; In toluene; at 120 ℃; for 24h;
DOI:10.1021/acs.orglett.0c02271

Reference yield:

: 491-35-0
C₆H₄NCH₂CHCCH₂

: 104-88-1
4-chlorobenzaldehyde

: 40317-03-1,4594-89-2
4-[(E)-2-(4-chlorophenyl)ethenyl]quinoline

Guidance literature:: With acetic anhydride;
DOI:10.1021/ja01192a009 DOI:10.1021/ja01301a044

Reference yield:

: 19343-78-3,74459-14-6
4-methyl-1,2,3,4-tetrahydroquinoline

: 4594-89-2
C₁₇H₁₂ClN

Guidance literature:: Multi-step reaction with 2 steps

1: nickel dibromide; potassium tert-butylate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 1,10-Phenanthroline; oxygen / tert-Amyl alcohol / 24 h / 95 °C

2: toluene-4-sulfonamide / toluene / 24 h / 120 °C

With 1,10-Phenanthroline; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium tert-butylate; oxygen; toluene-4-sulfonamide; nickel dibromide; In tert-Amyl alcohol; toluene;
DOI:10.1021/acs.orglett.0c02271