4-Hydroxytamoxifen acid

Base Information

Chemical Name:4-Hydroxytamoxifen acid
CAS No.:141777-00-6
Molecular Formula:C₂₄H₂₂O₄
Molecular Weight:374.436
Hs Code.:
Nikkaji Number:J354.279C,J506.551H
ChEMBL ID:CHEMBL106773
Mol file:141777-00-6.mol

Synonyms:4-Hydroxytamoxifen acid;141777-00-6;CHEMBL106773;2-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenoxy]acetic acid;SCHEMBL639683;BDBM50054811;2-[4-[1-(4-Hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]acetic acid;{4-[(Z)-1-(4-Hydroxy-phenyl)-2-phenyl-but-1-enyl]-phenoxy}-acetic acid

Suppliers and Price of 4-Hydroxytamoxifen acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Hydroxytamoxifen acid

Chemical Property:

PSA：66.76000
LogP:5.22470
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:374.15180918
Heavy Atom Count:28
Complexity:519

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCC(=O)O)C3=CC=CC=C3
Isomeric SMILES:CC/C(=C(\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCC(=O)O)/C3=CC=CC=C3

Technology Process of 4-Hydroxytamoxifen acid

There total 25 articles about 4-Hydroxytamoxifen acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 440646-12-8
(Z)-2-[4-[1-(4-(benzyloxy)phenyl)-2-phenyl-1-butenyl]phenoxy]acetic acid benzyl ester

: 141777-00-6
(Z)-2-[4-[1-(p-hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]acetic acid

Guidance literature:: With hydrogen; 10percent palladium on carbon; In methanol; ethyl acetate; for 0.666667h; under 760.051 Torr;
DOI:10.1021/jo0255328

Reference yield: 97.0%

: ethyl 2-(4-(1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl)phenoxy)acetate

: 141777-00-6
(E,Z)-4-<1-(p-hydroxyphenyl)-2-phenyl-1-butenyl>phenoxyacetic acid

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1021/jm501218e

Reference yield: 73.0%

: 185223-80-7
{4-[(Z)-1-(4-Benzyloxy-phenyl)-2-phenyl-but-1-enyl]-phenoxy}-acetic acid

: 141777-00-6
(E,Z)-4-<1-(p-hydroxyphenyl)-2-phenyl-1-butenyl>phenoxyacetic acid

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; for 11.5h; under 2275.5 Torr;
DOI:10.1021/jm960517e