Cinnamic acid, 2-cinnamamidoethyl ester

Base Information

• Chemical Name: Cinnamic acid, 2-cinnamamidoethyl ester
• CAS No.: 43196-28-7
• Molecular Formula: C20H19NO3
• Molecular Weight: 321.3698
• Nikkaji Number: J75.245B
• Wikidata: Q76326033
• Mol file: 43196-28-7.mol

Synonyms:CINNAMIC ACID, 2-CINNAMAMIDOETHYL ESTER;43196-28-7;2-[[(E)-3-phenylprop-2-enoyl]amino]ethyl (E)-3-phenylprop-2-enoate;BRN 2290931;2-Propenoic acid, 3-phenyl-, 2-((1-oxo-3-phenyl-2-propenyl)amino)ethyl ester;2-Propenoic acid, 3-phenyl-, 2-[(1-oxo-3-phenyl-2-propenyl)amino]ethyl ester;LS-54069;3-Phenylpropenoic acid 2-(3-phenylpropenoylamino)ethyl ester

Chemical Property of Cinnamic acid, 2-cinnamamidoethyl ester

Chemical Property:

• Vapor Pressure: 6.03E-13mmHg at 25°C
• Boiling Point: 568.7°Cat760mmHg
• PKA: 14.23±0.46(Predicted)
• Flash Point: 297.7°C
• Density: 1.169g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 321.13649347
• Heavy Atom Count: 24
• Complexity: 444

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)NCCOC(=O)C=CC2=CC=CC=C2
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C(=O)NCCOC(=O)/C=C/C2=CC=CC=C2

Technology Process of Cinnamic acid, 2-cinnamamidoethyl ester

There total 1 articles about Cinnamic acid, 2-cinnamamidoethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (E)-3-Phenyl-acrylic acid 2-[(Z)-(3-phenyl-acryloyl)amino]-ethyl ester (43196-28-7)

Guidance literature:

Reference yield: 62.0%

Togni's reagent II (887144-94-7) + (E)-3-Phenyl-acrylic acid 2-[(Z)-(3-phenyl-acryloyl)amino]-ethyl ester (43196-28-7) → C21H18F3NO3 (1568113-89-2)

Guidance literature:

With copper(l) iodide; In N,N-dimethyl-formamide; at 80 ℃; for 24h; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/ol5004498

Downstream raw materials:

C₂₁H₁₈F₃NO₃