[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl methanesulfonate

Base Information

• Chemical Name: [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl methanesulfonate
• CAS No.: 15147-67-8
• Molecular Formula: C₁₀H₁₄N₂O₈S
• Molecular Weight: 322.296
• Mol file: 15147-67-8.mol

Synonyms:SCHEMBL8930586

Chemical Property of [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl methanesulfonate

Chemical Property:

• Refractive Index: 1.616
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.676g/cm³
• XLogP3: -2.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 322.04708658
• Heavy Atom Count: 21
• Complexity: 568

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)OCC1C(C(C(O1)N2C=CC(=O)NC2=O)O)O
• Isomeric SMILES: CS(=O)(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)O)O

Technology Process of [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl methanesulfonate

There total 1 articles about [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5'-deoxy-2',3'-O-isopropylidene-5'-O-methanesulfonyl-uridine (15083-09-7) → 5'-O-mesyluridine (15147-67-8)

Guidance literature:

With hydrogenchloride; water; In methanol; at 20 ℃; Inert atmosphere;

DOI:10.1080/15257770903306625

upstream raw materials:

5'-deoxy-2',3'-O-isopropylidene-5'-O-methanesulfonyl-uridine

Refernces