Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide

Base Information

Chemical Name:Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide
CAS No.:77965-40-3
Molecular Formula:C₁₁H₁₇N₅O₂S
Molecular Weight:283.354
Hs Code.:
DSSTox Substance ID:DTXSID60228627
Nikkaji Number:J71.016D
Wikidata:Q83108657

Synonyms:BRN 5108655;Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide;77965-40-3;((6-Methyl-4-morpholino-2-pyrimidinyl)thio)acetic acid hydrazide;Acetic acid, ((4-methyl-6-(4-morpholinyl)-2-pyrimidinyl)thio)-, hydrazide;C11H17N5O2S;DTXSID60228627;C11-H17-N5-O2-S;(6-Methyl-4-morpholino-2-pyrimidinylthio)acetic acid hydrazide

Suppliers and Price of Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide

Chemical Property:

Vapor Pressure:2.76E-13mmHg at 25°C
Boiling Point:576.4°Cat760mmHg
Flash Point:302.4°C
Density:1.37g/cm³
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:283.11029598
Heavy Atom Count:19
Complexity:301

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)SCC(=O)NN)N2CCOCC2

Technology Process of Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide

There total 3 articles about Acetic acid, ((6-methyl-4-morpholino-2-pyrimidinyl)thio)-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 77940-22-8
(4-Methyl-6-morpholin-4-yl-pyrimidin-2-ylsulfanyl)-acetic acid methyl ester

: 77965-40-3
(4-Methyl-6-morpholin-4-yl-pyrimidin-2-ylsulfanyl)-acetic acid hydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 15 - 20 ℃; for 3h;
DOI:10.1007/BF00773091

Reference yield:

: 52026-43-4
4-(2-chloro-6-methylpyrimidin-4-yl)morpholine

: 77965-40-3
(4-Methyl-6-morpholin-4-yl-pyrimidin-2-ylsulfanyl)-acetic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / Et₃N / 3 h / Heating

2: 87 percent / hydrazine hydrate / ethanol / 3 h / 15 - 20 °C

With hydrazine hydrate; triethylamine; In ethanol;
DOI:10.1007/BF00773091

Reference yield:

: 84044-51-9
(6-Methyl-4-chloro-2-pyrimidinylthio)acetate

: 77965-40-3
(4-Methyl-6-morpholin-4-yl-pyrimidin-2-ylsulfanyl)-acetic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / Na₂CO₃ / methanol / 2 h / Heating

2: 87 percent / hydrazine hydrate / ethanol / 3 h / 15 - 20 °C

With sodium carbonate; hydrazine hydrate; In methanol; ethanol;
DOI:10.1007/BF00773091