7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one

Base Information

Chemical Name:7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one
CAS No.:112859-12-8
Molecular Formula:C20H19 N3 O4 S
Molecular Weight:397.455
Hs Code.:
UNII:ZC0V0RZ3CB
DSSTox Substance ID:DTXSID40150194
Nikkaji Number:J494.492E
Pharos Ligand ID:PJQX85GPUF4D
ChEMBL ID:CHEMBL88245

Synonyms:2H-Imidazo(4,5-b)quinolin-2-one, 1,3-dihydro-7-(4-(phenylsulfonyl)butoxy)-;7-(4-(phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one;BMY 21638;BMY-21638

Suppliers and Price of 7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one

Chemical Property:

Vapor Pressure:1.39E-13mmHg at 25°C
Boiling Point:583°Cat760mmHg
Flash Point:306.4°C
Density:1.351g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:397.10962727
Heavy Atom Count:28
Complexity:644

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)CCCCOC2=CC3=CC4=C(NC(=O)N4)N=C3C=C2

Technology Process of 7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one

There total 6 articles about 7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 5-[[2-nitro-5-[4-(phenylsulfonyl)butoxy]phenyl]methylene]-2,4-imidazolidinedione

: 112859-12-8
7-[4-(phenylsulfonyl)butoxy]-1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: With iodine; palladium on charcoal; In N-methyl-acetamide; methanol;

Reference yield: 51.0%

: 5-[2-Amino-5-(4-benzenesulfonyl-butoxy)-benzyl]-imidazolidine-2,4-dione

: 112859-12-8
7-[4-(phenylsulfonyl)butoxy]-1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: With iodine; In methanol; for 1h; Heating;
DOI:10.1021/jm00092a019

Reference yield:

: 42454-06-8
2-nitro-5-hydroxybenzaldehyde

: 112859-12-8
7-[4-(phenylsulfonyl)butoxy]-1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / K₂CO₃, KI / dimethylformamide / 4 h / Heating

2: 61 percent / EtONa / ethanol; CHCl₃ / 0.33 h

3: H₂ / 10 percent Pd/C / dimethylformamide / 3102.9 Torr

4: 51 percent / I₂ / methanol / 1 h / Heating

With hydrogen; iodine; sodium ethanolate; potassium carbonate; potassium iodide; palladium on activated charcoal; In methanol; ethanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm00092a019