2a,3,4,5-Tetrahydroacenaphthylene

Base Information

• Chemical Name: 2a,3,4,5-Tetrahydroacenaphthylene
• CAS No.: 16897-56-6
• Molecular Formula: C12H12
• Molecular Weight: 156.227
• Hs Code.: 2902909090
• European Community (EC) Number: 240-939-5
• DSSTox Substance ID: DTXSID10937570
• Nikkaji Number: J318.295I
• Mol file: 16897-56-6.mol

Synonyms:2a,3,4,5-Tetrahydroacenaphthylene;3,4,5,11-Tetrahydroacenaphthene;26761-12-6;16897-56-6;3,4,5,11-Thtrahydroacenaphthene;3,3a,4,5-tetrahydroacenaphthylene;EINECS 240-939-5;DTXSID10937570;FTHSEFQUTAMMGF-UHFFFAOYSA-N;6,7,8,8a-tetrahydroacenaphthylene;MFCD00143054;NS00052737;E78876

Chemical Property of 2a,3,4,5-Tetrahydroacenaphthylene

Chemical Property:

• Vapor Pressure: 0.00514mmHg at 25°C
• Boiling Point: 284.3°Cat760mmHg
• Flash Point: 122.5°C
• PSA: 0.00000
• Density: 1.088g/cm³
• LogP: 3.13330
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 156.093900383
• Heavy Atom Count: 12
• Complexity: 204

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2C=CC3=CC=CC(=C23)C1

Technology Process of 2a,3,4,5-Tetrahydroacenaphthylene

There total 5 articles about 2a,3,4,5-Tetrahydroacenaphthylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4,5,10-tetrahydroacenaphthene-1-one (63328-18-7) → 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline (16897-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: (i) Na, CS₂, (ii) MeI, (iii) (heating)

With sodium tetrahydroborate;

DOI:10.1021/jo01272a052

Reference yield:

2-(1,2,3,4-tetrahydronaphthalen-1-yl)acetic acid (63328-17-6,171227-58-0) → 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline (16897-56-6)

Guidance literature:

Multi-step reaction with 3 steps

1: polyphosphoric acid

2: NaBH₄

3: (i) Na, CS₂, (ii) MeI, (iii) (heating)

With sodium tetrahydroborate; PPA;

DOI:10.1021/jo01272a052

Reference yield:

(1,2,3,4-tetrahydro-[1]naphthyl)-malonic acid diethyl ester (63328-19-8) → 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline (16897-56-6)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) KOH, (ii) (heating)

2: polyphosphoric acid

3: NaBH₄

4: (i) Na, CS₂, (ii) MeI, (iii) (heating)

With sodium tetrahydroborate; PPA;

DOI:10.1021/jo01272a052

upstream raw materials:

2,3,4,5-tetrahydroacenaphthylen-1-ol

3,4,5,10-tetrahydroacenaphthene-1-one

2-(1,2,3,4-tetrahydronaphthalen-1-yl)acetic acid

(1,2,3,4-tetrahydro-[1]naphthyl)-malonic acid diethyl ester