(8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Base Information Edit

Chemical Name:(8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol
CAS No.:3625-82-9
Molecular Formula:C20H28O2
Molecular Weight:300.441
Hs Code.:
European Community (EC) Number:609-222-8,617-629-7
DSSTox Substance ID:DTXSID801036252
Wikidata:Q76005670
Mol file:3625-82-9.mol

Synonyms:18-ME-3-ME;18-methylestradiol-3-methyl ether

Suppliers and Price of (8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
3-Methoxy-18-methyl-1,3,5(10)-estratrien-17β-ol
5 mg
$ 925.00

Total 3 raw suppliers

Chemical Property of (8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol Edit

Chemical Property:

Vapor Pressure:1.43E-08mmHg at 25°C
Boiling Point:441.4°Cat760mmHg
Flash Point:192°C
PSA：29.46000
Density:1.089g/cm³
LogP:4.30230
Water Solubility.:4mg/L at 20℃
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:300.208930132
Heavy Atom Count:22
Complexity:409

Purity/Quality:

99.9% ^*data from raw suppliers

3-Methoxy-18-methyl-1,3,5(10)-estratrien-17β-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC
Isomeric SMILES:CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC
Uses 18-methylestradiol-3-methyl ether is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.

Technology Process of (8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

There total 26 articles about (8R,9S,13S,14S,17S)-13-ethyl-3-methoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 162210-67-5
D-(+)-13β-ethyl-3-methoxygona-1,3,5(10)-trien-17β-yl trifluoroacetate

: 3625-82-9
(+)-17β-hydroxy-13β-ethyl-3-methoxygona-1,3,5(10)-triene

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; methanol; for 1h; Ambient temperature;
DOI:10.1016/0039-128X(94)90017-5

Reference yield:

: 3-methoxy-18-methyl-1,3,5(10),8-estratetraen-17β-ol

: 3625-82-9
(+)-17β-hydroxy-13β-ethyl-3-methoxygona-1,3,5(10)-triene

Guidance literature:: 3-methoxy-18-methyl-1,3,5(10),8-estratetraen-17β-ol; With ammonia; lithium; aniline; In tetrahydrofuran; at -48 - -35 ℃;

With 4-methyl-pent-3-en-2-one; In tetrahydrofuran;