15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate

Base Information

Chemical Name:15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate
CAS No.:77620-57-6
Molecular Formula:C₁₉H₂₁ClO₈
Molecular Weight:412.824
Hs Code.:

Synonyms:

Suppliers and Price of 15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of 15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate

Chemical Property:

Vapor Pressure:3.75E-12mmHg at 25°C
Boiling Point:550.2°Cat760mmHg
Flash Point:204.4°C
Density:1.44g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate

There total 7 articles about 15-(acetyloxy)-3,8-dioxo-12,13-epoxytrichothec-9-en-4-yl chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 77620-56-5
15-acetoxy-4β-(chloroacetoxy)scirpene-3α,8β-diol

: 77620-57-6
15-acetoxy-4β-(chloroacetoxy)scirpene-3,8-dione

Guidance literature:: With dimethyl sulfoxide; trifluoroacetic anhydride; In dichloromethane; at -78 ℃; for 0.5h;
DOI:10.1021/jm00347a018

Reference yield:

: 77620-56-5
15-acetoxy-4β-chloroacetoxy-3α,8β-dihydroxy-12,13-epoxytrichothec-9-ene

: 77620-57-6
15-Acetoxy-4β-chloroacetoxy-12,13-epoxytrichothec-9-en-3,8-dione

Guidance literature:: With dimethyl sulfoxide; triethylamine; trifluoroacetic anhydride; In dichloromethane;

Reference yield:

: 2270-40-8,106454-36-8,28776-47-8
anguidine

: 77620-57-6
15-acetoxy-4β-(chloroacetoxy)scirpene-3,8-dione

Guidance literature:: Multi-step reaction with 6 steps

1: 72 percent / p-toluenesulfonic acid / CH₂Cl₂ / 2 h / Ambient temperature

2: 38 percent / aq. NH₄OH / methanol; tetrahydrofuran / 168 h / Ambient temperature

3: 83 percent / pyridine / CH₂Cl₂ / 64 h / Ambient temperature

4: 80 percent / 10percent aq. HCl / aq. ethanol / 40 h / Ambient temperature

5: 42 percent / SeO₂ / dioxane; H₂O / 24 h / Heating

6: 66 percent / Me₂SO, trifluoroacetic anhydride / CH₂Cl₂ / 0.5 h / -78 °C

With pyridine; hydrogenchloride; ammonium hydroxide; selenium(IV) oxide; toluene-4-sulfonic acid; dimethyl sulfoxide; trifluoroacetic anhydride; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; water;
DOI:10.1021/jm00347a018