DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide

Base Information

Chemical Name:DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide
CAS No.:149206-86-0
Molecular Formula:C31H46 N10 O13
Molecular Weight:766.76
Hs Code.:
Mol file:149206-86-0.mol

Synonyms:1,4,7,10-Tetraazacyclododecane,L-phenylalaninamide deriv.

Suppliers and Price of DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide

Chemical Property:

PSA：344.13000
LogP:-0.73230

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide

There total 4 articles about DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (4,7-Bis-tert-butoxycarbonylmethyl-10-{[({[({[(S)-1-carbamoyl-2-(4-nitro-phenyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-methyl}-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid tert-butyl ester

: 149206-86-0
(4-{[({[({[(S)-1-Carbamoyl-2-(4-nitro-phenyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-methyl}-7,10-bis-carboxymethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid

Guidance literature:: With trifluoroacetic acid; at 0 ℃;

Reference yield:

: 294-90-6
1,4,7,10-tetraazacyclododecan

: 149206-86-0
(4-{[({[({[(S)-1-Carbamoyl-2-(4-nitro-phenyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-methyl}-7,10-bis-carboxymethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / Ambient temperature

2: K₂CO₃, TBACl / dimethylformamide / 2 h / Ambient temperature

3: 0.28 g / TFA / 0 °C

With tetrabutyl-ammonium chloride; potassium carbonate; trifluoroacetic acid; In N,N-dimethyl-formamide;

Reference yield:

: (S)-2-(2-{2-[2-(2-Bromo-acetylamino)-acetylamino]-acetylamino}-acetylamino)-3-(4-nitro-phenyl)-propionamide

: 149206-86-0
(4-{[({[({[(S)-1-Carbamoyl-2-(4-nitro-phenyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-methyl}-7,10-bis-carboxymethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / Ambient temperature

2: K₂CO₃, TBACl / dimethylformamide / 2 h / Ambient temperature

3: 0.28 g / TFA / 0 °C

With tetrabutyl-ammonium chloride; potassium carbonate; trifluoroacetic acid; In N,N-dimethyl-formamide;