Technology Process of 2,5-Heptadienoic acid,7-(benzoyloxy)-4-oxo-, methyl ester, (2E,5E)-
There total 13 articles about 2,5-Heptadienoic acid,7-(benzoyloxy)-4-oxo-, methyl ester, (2E,5E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
acetonitrile;
at 20 ℃;
for 3h;
Overall yield = 51 percent; Overall yield = 84 mg; stereoselective reaction;
Inert atmosphere;
DOI:10.1039/d1ob00599e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 82 percent / pyridine, DMAP / CH2Cl2 / 24 h / Ambient temperature
2: 70 percent / H2, AcOH, H2O / W2 Ni-Raney / methanol / 4 h
3: 1.) MeSO2Cl, Et3N 2.) Et3N / 1.) CH2Cl2, 0 deg C and room t., 1 h, 2.) CH2Cl2, 0 deg C and room t., 30 min
With
pyridine; dmap; water; hydrogen; acetic acid; methanesulfonyl chloride; triethylamine;
W2 Ni-Raney;
In
methanol; dichloromethane;
DOI:10.1016/S0040-4020(01)89589-2
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / p-TsOH / methanol / 0.5 h / Ambient temperature
2: 82 percent / pyridine, DMAP / CH2Cl2 / 24 h / Ambient temperature
3: 70 percent / H2, AcOH, H2O / W2 Ni-Raney / methanol / 4 h
4: 1.) MeSO2Cl, Et3N 2.) Et3N / 1.) CH2Cl2, 0 deg C and room t., 1 h, 2.) CH2Cl2, 0 deg C and room t., 30 min
With
pyridine; dmap; water; hydrogen; toluene-4-sulfonic acid; acetic acid; methanesulfonyl chloride; triethylamine;
W2 Ni-Raney;
In
methanol; dichloromethane;
DOI:10.1016/S0040-4020(01)89589-2
