Nickel,N',O-, (OC-6-33')-

Base Information

• Chemical Name: Nickel,N',O-, (OC-6-33')-
• CAS No.: 38966-31-3
• Molecular Formula: C22H28N4NiO2+2
• Molecular Weight: 439.1756
• NSC Number: 150495
• Mol file: 38966-31-3.mol

Synonyms:NSC150495;38966-31-3;Nickel,N',O-, (OC-6-33')-;NSC-150495;Nickel,N',O]-, (OC-6-33')-

Chemical Property of Nickel,N',O-, (OC-6-33')-

Chemical Property:

• Vapor Pressure: 5.67E-05mmHg at 25°C
• Boiling Point: 346.7°Cat760mmHg
• Flash Point: 163.5°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 438.156568
• Heavy Atom Count: 29
• Complexity: 453

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN1CCN=CC2=CC=CC=C2O.C1CN1CCN=CC2=CC=CC=C2O.[Ni+2]

Technology Process of Nickel,N',O-, (OC-6-33')-

There total 1 articles about Nickel,N',O-, (OC-6-33')- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-(2-amino-ethyl)-aziridine (4025-37-0) + bis(salicylaldehyde)-nickel(II)-dihydrate (15379-71-2,22578-24-1,60490-60-0,43190-64-3) → bis[N-[2-(1-aziridinyl)ethyl]salicylaldimino]nickel(II) (38966-31-3)

Guidance literature:

In methanol; diethyl ether; ligand was added to soln. of Ni complex with stirring; stirring at roomtemp. for 12 h; evapn., filtration, washing with aq. NaOH, Et2O; recrystn. (CH2Cl2), drying in vac.;

DOI:10.1021/ic50224a083

Reference yield:

bissalicyladimino>nickel(II) (38966-31-3) → 2-{[(E)-2-Aziridin-1-yl-ethylimino]-methyl}-phenol (78186-32-0) + 1,2,3,5,6,11b-hexahydroimidazo<1,2-d><1,4>benzoxazepine (77123-89-8)

Guidance literature:

With potassium hydroxide; hydrogen bromide; trisodium Edetate; Multistep reaction; 1.) MeCN, reflux, 1.5 h, 2.) H₂O, room temp., 1 h;

DOI:10.1021/jo00324a043

Reference yield:

potassium cyanide (151-50-8) + bissalicyladimino>nickel(II) (38966-31-3) → 2-{[(E)-2-Aziridin-1-yl-ethylimino]-methyl}-phenol (78186-32-0) + 1,2,3,5,6,11b-hexahydroimidazo<1,2-d><1,4>benzoxazepine (77123-89-8) + 4-(2-{[1-(2-Hydroxy-phenyl)-meth-(E)-ylidene]-amino}-ethyl)-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine-5-carbonitrile (77123-90-1)

Guidance literature:

With hydrogen bromide; Multistep reaction; 1.) MeCN, reflux, 1.5 h, 2.) CHCl₃, H₂O, 1 h;

DOI:10.1021/jo00324a043

upstream raw materials:

1-(2-amino-ethyl)-aziridine

bis(salicylaldehyde)-nickel(II)-dihydrate

Downstream raw materials:

2-{[(E)-2-Aziridin-1-yl-ethylimino]-methyl}-phenol

1,2,3,5,6,11b-hexahydroimidazo<1,2-d><1,4>benzoxazepine

4-(2-{[1-(2-Hydroxy-phenyl)-meth-(E)-ylidene]-amino}-ethyl)-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine-5-carbonitrile

Refernces