Radium-223

Base Information

• Chemical Name: Radium-223
• CAS No.: 15623-45-7
• Molecular Formula: Ra
• Molecular Weight: 224
• UNII: 8BR2SOL3L1
• DSSTox Substance ID: DTXSID30912344
• Wikidata: Q27270150
• ChEMBL ID: CHEMBL4297420
• Mol file: 15623-45-7.mol

Synonyms:223Ra radioisotope;Ra-223 radioisotope;Radium-223

Chemical Property of Radium-223

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 223.01850
• Heavy Atom Count: 1
• Complexity: 0

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [Ra]
• Isomeric SMILES: [223Ra]
• Recent ClinicalTrials: Radium-223 in Biochemically Recurrent Prostate Cancer
• Recent EU Clinical Trials: Randomized, multicentre phase II trial of the sequencing of Radium-223 and Docetaxel plus prednisone in symptomatic bone-only metastatic castration-resistant prostate cancer (mCRPC)

Technology Process of Radium-223

There total 5 articles about Radium-223 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Thorium X (2+) (13233-32-4,13981-53-8,15262-20-1,15623-45-7,15756-71-5) → (224)Radium (13233-32-4,13981-53-8,15262-20-1,15623-45-7,15756-71-5)

Guidance literature:

In ammonia; Electrochem. Process; with or without electrical current;;

Reference yield:

(224)Ra(2+)*2NO3(1-)=(224)Ra(NO3)2 → (224)Radium (13233-32-4,13981-53-8,15262-20-1,15623-45-7,15756-71-5)

Guidance literature:

In nitric acid; Electrolysis; dissolution of Ra(NO3)2 in aq. HNO3, electrolysis under 12 V on Pt electrode; removal of electrode, drying for 2 h in air;

DOI:10.1021/ja068639b

Reference yield:

radium chloride → radium (13233-32-4,13981-53-8,15262-20-1,15623-45-7,15756-71-5)

Guidance literature:

In not given; Electrolysis; soln. of 0.106 g RaCl2; 10 g of pure Hg used as cathode; liquid amalgame dried and distilled in H-atmosphere; heated to 700 °C;; purified by sublimation in vac.;;

upstream raw materials:

Thorium X (2+)