2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate

Base Information

• Chemical Name: 2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate
• CAS No.: 131766-73-9
• Molecular Formula: C11H20O3
• Molecular Weight: 200.27
• Mol file: 131766-73-9.mol

Synonyms:2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate;2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetat;A mixture of: trans-4-acetoxy-4-methyl-2-propyl-tetrahydro-2H-pyran cis-4-acetoxy-4-methyl-2-propyl-tetrahydro-2H-pyran

Chemical Property of 2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate

Chemical Property:

• Vapor Pressure: 42.85Pa at 25℃
• Boiling Point: 248.3±33.0 °C(Predicted)
• Density: 0.98±0.1 g/cm3(Predicted)
• Water Solubility.: 2.5g/L at 20℃

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 24-37

MSDS Files:

Useful:

Technology Process of 2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate

There total 22 articles about 2H-Pyran-4-ol, tetrahydro-4-methyl-2-propyl-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1-buten-4-ol (763-32-6) + acetic anhydride (108-24-7) + butyraldehyde (123-72-8) → (2S,4R)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0) + (2R,4R)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0)

Guidance literature:

2-methyl-1-buten-4-ol; butyraldehyde; With Graphite; (R)-10-camphorsulfonic acid; at 20 ℃; for 2h;

acetic anhydride; for 4h; Temperature; Overall yield = 67 %; Overall yield = 29.5 g;

Reference yield:

2-methyl-1-buten-4-ol (763-32-6) + acetic anhydride (108-24-7) + butyraldehyde (123-72-8) → (2S,4R)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0) + (2R,4R)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0)

Guidance literature:

2-methyl-1-buten-4-ol; butyraldehyde; With Graphite; (R)-10-camphorsulfonic acid; at 20 ℃; for 2h;

acetic anhydride; for 4h; Temperature; Overall yield = 67 %; Overall yield = 29.5 g;

Reference yield:

2-methyl-1-buten-4-ol (763-32-6) + acetic anhydride (108-24-7) + butyraldehyde (123-72-8) → (2S,4S)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0) + (2R,4S)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol acetate (131766-73-9,723340-63-4,723340-89-4,723340-92-9,723340-93-0)

Guidance literature:

2-methyl-1-buten-4-ol; butyraldehyde; With Graphite; (1S)-10-camphorsulfonic acid; at 20 ℃; for 2h;

acetic anhydride; for 3h; Overall yield = 71 %; Overall yield = 31.24 g;

upstream raw materials:

acetic anhydride

(2S,4S)-tetrahydro-4-methyl-2-propyl-2H-pyran-4-ol

(3RS,5S)-3-methyloctane-1,3,5-triol

(3RS,5S)-3-methyloctane-1,3,5-triol 5-acetate