Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-

Base Information

Chemical Name:Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-
CAS No.:57334-90-4
Molecular Formula:C₂₂H₂₆ClN₃O₅S
Molecular Weight:479.985
Hs Code.:
DSSTox Substance ID:DTXSID201119048

Synonyms:57334-90-4;Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-;SCHEMBL25184898;BDBM631284;DTXSID201119048;US20230348371, Compound 1;CID 15453844;5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-hydroxybenzamide;5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxybenzamide

Suppliers and Price of Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:479.1281698
Heavy Atom Count:32
Complexity:730

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)NS(=O)(=O)C2=CC=C(C=C2)CCNC(=O)C3=C(C=CC(=C3)Cl)O

Technology Process of Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy-

There total 7 articles about Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 3173-53-3
Cyclohexyl isocyanate

: 4-[β-(2-hydroxy-5-chlorobenzene carboxamido)ethyl]benzene-sulfonamide

: 57334-90-4
N-{4-[β-(2-hydroxy-5-chlorobenzene carboxamido)ethyl]benzene-sulfonyl}-N'-cyclohexylurea

: 4363-89-7
cyclohexyl carbamic acid

Guidance literature:: With sodium hydroxide; at 20 ℃;
DOI:10.1002/jlcr.438

Reference yield:

: 10238-21-8
Glibenclamid

: 57334-90-4
N-{4-[β-(2-hydroxy-5-chlorobenzene carboxamido)ethyl]benzene-sulfonyl}-N'-cyclohexylurea

Guidance literature:: With boron tribromide;

Reference yield:

: 3173-53-3
Cyclohexyl isocyanate

: acetic acid 4-chloro-2-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-phenyl ester

: 57334-90-4
N-{4-[β-(2-hydroxy-5-chlorobenzene carboxamido)ethyl]benzene-sulfonyl}-N'-cyclohexylurea

Guidance literature:: Cyclohexyl isocyanate; acetic acid 4-chloro-2-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-phenyl ester;

With sodium methylate;