2-methyl-6-pentylpyridine

Base Information

• Chemical Name: 2-methyl-6-pentylpyridine
• CAS No.: 5394-28-5
• Molecular Formula: C11H17N
• Molecular Weight: 163.2594
• Mol file: 5394-28-5.mol

Synonyms:

Chemical Property of 2-methyl-6-pentylpyridine

Chemical Property:

• Vapor Pressure: 0.149mmHg at 25°C
• Boiling Point: 222.7°Cat760mmHg
• Flash Point: 81.7°C
• Density: 0.9g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-6-pentylpyridine

There total 4 articles about 2-methyl-6-pentylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-Heptanol (52390-72-4,543-49-7) + 2-aminobutanol (2867-59-6) → 2-methyl-6-pentylpyridine (5394-28-5)

Guidance literature:

With C₁₇H₁₁Cl₂N₃O₃Ru; potassium tert-butylate; In toluene; at 110 ℃; for 6h;

DOI:10.1021/acs.organomet.8b00359

Reference yield:

2-methyl-6-pentyl-nicotinic acid ethyl ester → 2-methyl-6-pentylpyridine (5394-28-5)

Guidance literature:

With sodium hydroxide; Erhitzen des Reaktionsprodukts mit Natronkalk auf 300grad;

Reference yield:

(E)-1-chloro-oct-1-en-3-one (39198-04-4) → 2-methyl-6-pentylpyridine (5394-28-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; aqueous NH₃

2: ethanolic NaOH-solution / Erhitzen des Reaktionsprodukts mit Natronkalk auf 300grad

With ammonium hydroxide; sodium hydroxide; ethanol;

upstream raw materials:

(E)-1-chloro-oct-1-en-3-one

2-Heptanol

2-aminobutanol