1-(2,4-Dichlorophenyl)-3-phenylurea

Base Information

• Chemical Name: 1-(2,4-Dichlorophenyl)-3-phenylurea
• CAS No.: 13142-54-6
• Molecular Formula: C₁₃H₁₀Cl₂N₂O
• Molecular Weight: 281.141
• European Community (EC) Number: 667-671-5
• NSC Number: 190581
• DSSTox Substance ID: DTXSID20307265
• Nikkaji Number: J1.063.023A
• Wikidata: Q82054633
• Mol file: 13142-54-6.mol

Synonyms:1-(2,4-dichlorophenyl)-3-phenylurea;13142-54-6;N-(2,4-dichlorophenyl)-N'-phenylurea;NSC190581;DTXSID20307265;STK413307;AKOS002665713;NSC-190581

Chemical Property of 1-(2,4-Dichlorophenyl)-3-phenylurea

Chemical Property:

• Vapor Pressure: 0.000488mmHg at 25°C
• Boiling Point: 313.7°Cat760mmHg
• Flash Point: 143.5°C
• Density: 1.45g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 280.0170183
• Heavy Atom Count: 18
• Complexity: 282

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)NC2=C(C=C(C=C2)Cl)Cl

Technology Process of 1-(2,4-Dichlorophenyl)-3-phenylurea

There total 5 articles about 1-(2,4-Dichlorophenyl)-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,4-dichlorophenyl)-N'-phenylthiourea (13528-25-1) → N-(2,4-dichloro-phenyl)-N'-phenyl-urea (13142-54-6)

Guidance literature:

With potassium bromate; sodium hydroxide;

DOI:10.1021/ja01350a023

Reference yield:

2,4-Dichloroaniline (554-00-7,51908-09-9) → N-(2,4-dichloro-phenyl)-N'-phenyl-urea (13142-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene

2: potassium bromate; aqueous NaOH-solution

With potassium bromate; sodium hydroxide; toluene;

DOI:10.1021/ja01350a023

Reference yield:

phenyl isothiocyanate (103-72-0) → N-(2,4-dichloro-phenyl)-N'-phenyl-urea (13142-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene

2: potassium bromate; aqueous NaOH-solution

With potassium bromate; sodium hydroxide; toluene;

DOI:10.1021/ja01350a023

upstream raw materials:

N-(2,4-dichlorophenyl)-N'-phenylthiourea

2,4-Dichloroaniline

phenyl isocyanate

benzoyl azide