PULCHINENOSIDE B4

Base Information

• Chemical Name: PULCHINENOSIDE B4
• CAS No.: 129741-57-7
• Molecular Formula: C₅₉H₉₆O₂₆
• Molecular Weight: 1221.4
• Mol file: 129741-57-7.mol

Synonyms:2)-a-L-arabinopyranosyl]-28-O-[a-L-rhamnopyranosyl-(1?;6)-b-D-glucopyranosyl]-3b,23-dihydroxylup-20(29)-en-28-oic acid;Anemoside B4;Chinensioside A;Pulchinenoside C;

Chemical Property of PULCHINENOSIDE B4

Chemical Property:

• Melting Point: 208-215 °C
• PKA: 12.50±0.70(Predicted)
• PSA: 412.82000
• Density: 1.48 g/cm³
• LogP: -2.68850

Purity/Quality:

95%-98% ^*data from raw suppliers

Anemoside B4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.
• Uses: Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory.