Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate

Base Information

Chemical Name:Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate
CAS No.:212329-37-8
Molecular Formula:C23H29NO3S
Molecular Weight:399.5463
Hs Code.:
UNII:6D9Q2QUU75
DSSTox Substance ID:DTXSID501017166
Nikkaji Number:J1.012.203A
Wikidata:Q27087764
Pharos Ligand ID:DY858QYZZF7Q
ChEMBL ID:CHEMBL111545
Mol file:212329-37-8.mol

Synonyms:2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate;MRS 1523

Suppliers and Price of Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
MRS 1523
5mg
$ 175.00

TRC
MRS 1523
10mg
$ 280.00

Sigma-Aldrich
MRS 1523 >98% (HPLC)
5mg
$ 249.00

Sigma-Aldrich
MRS 1523 >98% (HPLC)
25mg
$ 992.00

Cayman Chemical
MRS 1523 ≥98%
10mg
$ 310.00

Cayman Chemical
MRS 1523 ≥98%
25mg
$ 713.00

Cayman Chemical
MRS 1523 ≥98%
5mg
$ 167.00

Cayman Chemical
MRS 1523 ≥98%
1mg
$ 49.00

Biosynth Carbosynth
MRS 1523
10 mg
$ 210.00

Biosynth Carbosynth
MRS 1523
5 mg
$ 115.00

Total 7 raw suppliers

Chemical Property of Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate

Chemical Property:

Vapor Pressure:3.37E-12mmHg at 25°C
Boiling Point:551.3°C at 760 mmHg
PKA:1.44±0.28(Predicted)
Flash Point:287.2°C
PSA：81.56000
Density:1.1g/cm³
LogP:5.72360
Storage Temp.:2-8°C
Solubility.:DMSO: >10 mg/mL
XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:399.18681496
Heavy Atom Count:28
Complexity:492

Purity/Quality:

97% ^*data from raw suppliers

MRS 1523 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCC1=C(C(=NC(=C1C(=O)SCC)CC)C2=CC=CC=C2)C(=O)OCCC
Description MRS1523 is a selective adenosine A3 receptor antagonist (Kis = 18.9 and 113 nM for human and rat A3 receptors, respectively, versus Kis = 15.6 and 2.05 μM for rat A1 and A2A receptors, respectively). As activation of the A3 receptor is linked to several second messenger systems for signaling pathways involving inflammatory, asthmatic, and ischemic responses, this selective antagonist may be useful in characterizing the various functions of the receptor.
Uses MRS 1523 is a selective A3 adenosine receptor (A3AR) antagonist in human and rat.

Technology Process of Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate

There total 2 articles about Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%