N-phenyl-2-quinolinamine

Base Information

• Chemical Name: N-phenyl-2-quinolinamine
• CAS No.: 5468-85-9
• Molecular Formula: C15H12N2
• Molecular Weight: 220.274
• Hs Code.: 2933499090
• Mol file: 5468-85-9.mol

Synonyms:N-phenyl-2-aminoquinoline;2-anilinoquinoline;phenyl-2-quinolylamine;phenyl-quinolin-2-yl-amine;[2]Chinolyl-phenyl-amin;2-(phenylamino)quinoline;[2]quinolyl-phenyl-amine;N-phenyl-2-quinolinamine;

Chemical Property of N-phenyl-2-quinolinamine

Chemical Property:

• PSA: 24.92000
• Density: 1.15g/cm³
• LogP: 4.05140

Purity/Quality:

N-PHENYL-2-QUINOLINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-phenyl-2-quinolinamine

There total 31 articles about N-phenyl-2-quinolinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Chloroquinoline (612-62-4) + aniline (62-53-3) → N-phenylquinolin-2-amine (5468-85-9)

Guidance literature:

at 160 ℃; for 6h; Inert atmosphere; Neat (no solvent);

DOI:10.1002/chem.201100574

Reference yield: 95.0%

2-bromoquinoline (2005-43-8) + aniline (62-53-3) → N-phenylquinolin-2-amine (5468-85-9)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium tert-butylate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In 1,4-dioxane; at 100 ℃; Inert atmosphere;

DOI:10.1021/ja1067993

Reference yield: 85.0%

Quinoline N-oxide (1613-37-2) + 1,3-Diphenylcarbodiimide (622-16-2) → N-phenylquinolin-2-amine (5468-85-9)

Guidance literature:

at 130 ℃; for 12h;

DOI:10.1021/acs.joc.1c00741

upstream raw materials:

2-Chloroquinoline

sodium anilide

aniline

(4-chloro-quinolin-2-yl)-phenyl-amine

Downstream raw materials:

2,4-Diphenyl-2,3-dihydro-1H-pyrimido<3,4-a>chinolin-1,3-dion

4-Benzyl-2-phenyl-2,3-dihydro-1H-pyrimido<3,4-a>chinolin-1,3-dion

2-Benzyl-1-oxo-4-phenyl-1H-pyrimido<1,2-a>chinolin-4-ium-3-olat

6H-quinindoline