2,6-Di-morpholin-4-yl-7H-purine

Base Information

Chemical Name:2,6-Di-morpholin-4-yl-7H-purine
CAS No.:7494-71-5
Molecular Formula:C13H18N6O2
Molecular Weight:290.321
Hs Code.:
ChEMBL ID:CHEMBL4100890
DSSTox Substance ID:DTXSID50996444
Nikkaji Number:J954.715K
NSC Number:401290

Synonyms:CHEMBL4100890;7494-71-5;2,6-bismorpholinopurine;SCHEMBL3322529;DTXSID50996444;QOMAEQWURQWFMP-UHFFFAOYSA-N;2,6-Di-morpholin-4-yl-7H-purine;BDBM50266527;NSC401290;2,6-Bis(morpholin-4-yl)-9H-purine;NSC-401290;5247-13-2

Suppliers and Price of 2,6-Di-morpholin-4-yl-7H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2,6-Di-morpholin-4-yl-7H-purine

Chemical Property:

Vapor Pressure:2.16E-08mmHg at 25°C
Boiling Point:452.9°Cat760mmHg
Flash Point:227.7°C
Density:1.6g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:290.14912384
Heavy Atom Count:21
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NC(=NC3=C2NC=N3)N4CCOCC4

Technology Process of 2,6-Di-morpholin-4-yl-7H-purine

There total 4 articles about 2,6-Di-morpholin-4-yl-7H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 110-91-8,99108-56-2
morpholine

: 5451-40-1
2,6-dichloro-7H-purine

: 7494-71-5
2,6-dimorpholino-7(9)H-purine

Guidance literature:: at 120 ℃; for 5h;

Reference yield: 57.0%

: 110-91-8,99108-56-2
morpholine

: 4010-81-5
4-(2-chloro-9H-purin-6-yl)morpholine

: 7494-71-5
4,4'-(9H-purine-2,6-diyl)dimorpholine

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 150 ℃; for 30h;
DOI:10.1016/S0040-4039(98)00098-7

Reference yield:

: 5451-40-1
2,6 dichloropurine

: 7494-71-5
4,4'-(9H-purine-2,6-diyl)dimorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / dimethylformamide / 80 - 100 °C

2: 57 percent / Et₃N / dimethylformamide / 30 h / 150 °C

With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(98)00098-7