Technology Process of Methyl 4-phenanthrenecarboxylate
There total 4 articles about Methyl 4-phenanthrenecarboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: EtN-(i-Pr)2 / CH2Cl2 / 16 h / -78 - 20 °C
1.2: RhCl3 / ethanol / 3.5 h / Heating
2.1: t-BuOK / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 17 h / Heating
2.2: second generation Grubbs catalyst / CH2Cl2 / 18 h / Heating
With
potassium tert-butylate; N-ethyl-N,N-diisopropylamine;
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1016/j.tetlet.2005.07.084
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: K2CO3 / acetone / 16 h / Heating
1.2: 3 h / 210 °C
2.1: EtN-(i-Pr)2 / CH2Cl2 / 16 h / -78 - 20 °C
2.2: RhCl3 / ethanol / 3.5 h / Heating
3.1: t-BuOK / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 17 h / Heating
3.2: second generation Grubbs catalyst / CH2Cl2 / 18 h / Heating
With
potassium tert-butylate; potassium carbonate; N-ethyl-N,N-diisopropylamine;
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane; dichloromethane; water; acetone;
DOI:10.1016/j.tetlet.2005.07.084
- Guidance literature:
-
3-((E)-Propenyl)-2-trifluoromethanesulfonyloxy-benzoic acid methyl ester; 2-vinylbenzeneboronic acid;
With
potassium tert-butylate;
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane; water;
for 17h;
Heating;
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
dichloromethane;
for 18h;
Heating;
DOI:10.1016/j.tetlet.2005.07.084
