2-Amino-4'-bromopropiophenone hydrochloride

Base Information

Chemical Name:2-Amino-4'-bromopropiophenone hydrochloride
CAS No.:87124-01-4
Molecular Formula:C₉H₁₀BrNO*ClH
Molecular Weight:264.549
Hs Code.:
DSSTox Substance ID:DTXSID501007353

Synonyms:87124-01-4;2-Amino-4'-bromopropiophenone hydrochloride;2-amino-1-(4-bromophenyl)propan-1-one hydrochloride;4-Bromo-alpha-aminopropiophenone hydrochloride;Propiophenone, 2-amino-4'-bromo-, hydrochloride;2-amino-1-(4-bromophenyl)propan-1-one;hydrochloride;1-Propanone, 2-amino-1-(4-bromophenyl)-, hydrochloride;C9H10BrNO.ClH;C9-H10-Br-N-O.Cl-H;SCHEMBL10810636;DTXSID501007353;LS-125037;CS-0235624;EN300-1590467;2-Amino-1-(4-bromophenyl)propan-1-one--hydrogen chloride (1/1)

Suppliers and Price of 2-Amino-4'-bromopropiophenone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Amino-4'-bromopropiophenone hydrochloride

Chemical Property:

Vapor Pressure:0.000221mmHg at 25°C
Boiling Point:326.1°Cat760mmHg
Flash Point:151°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.97125
Heavy Atom Count:13
Complexity:164

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1=CC=C(C=C1)Br)N.Cl

Technology Process of 2-Amino-4'-bromopropiophenone hydrochloride

There total 3 articles about 2-Amino-4'-bromopropiophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 875289-85-3
2-azido-1-(4-bromobenzene)-1-propanone

: 87124-01-4
2-amino-1-(4-bromo-phenyl)-propan-1-one; hydrochloride

Guidance literature:: 2-azido-1-(4-bromobenzene)-1-propanone; With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 1h;

With hydrogenchloride; In methanol;
DOI:10.1039/d0nj05065b

Reference yield:

: 38786-67-3
2-bromo-1-(4-bromophenyl)propan-1-one

: 87124-01-4
2-amino-1-(4-bromo-phenyl)-propan-1-one; hydrochloride

Guidance literature:: 2-Bromo-4'-bromopropiophenone; With diformylimide sodium salt; In acetonitrile; at 75 ℃; for 4h;

With hydrogenchloride; In water monomer; for 1h; Reflux;
DOI:10.1080/14756366.2022.2053524

Reference yield:

: 10342-83-3
4'-Bromopropiophenone

: 87124-01-4
2-amino-1-(4-bromo-phenyl)-propan-1-one; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: copper(ll) bromide / ethyl acetate / 4 h / Reflux

2: sodium azide / acetone / 3 h / 20 °C / Inert atmosphere

3: hydrogen; palladium 10% on activated carbon / methanol / 1 h / 20 °C

With sodium azide; palladium 10% on activated carbon; hydrogen; copper(ll) bromide; In methanol; ethyl acetate; acetone;
DOI:10.1039/d0nj05065b