Meconic acid

Base Information

Chemical Name:Meconic acid
CAS No.:497-59-6
Molecular Formula:C7H4 O7
Molecular Weight:200.105
Hs Code.:
European Community (EC) Number:207-848-2
NSC Number:805
UNII:V502I79516
DSSTox Substance ID:DTXSID2060096,DTXSID20901328
Nikkaji Number:J6.102F
Wikipedia:Meconic_acid
Wikidata:Q421116
Metabolomics Workbench ID:46159
ChEMBL ID:CHEMBL109516
Mol file:497-59-6.mol

Synonyms:meconic acid

Suppliers and Price of Meconic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
MeconicAcid
25mg
$ 180.00

Medical Isotopes, Inc.
MeconicAcid
250 mg
$ 650.00

American Custom Chemicals Corporation
3-HYDROXY-4-OXO-4H-PYRAN-2,6-DICARBOXYLIC ACID 95.00%
5MG
$ 498.36

Total 9 raw suppliers

Chemical Property of Meconic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:120°C (rough estimate)
Refractive Index:1.4455 (estimate)
Boiling Point:353.8°Cat760mmHg
PKA:0.60±0.40(Predicted)
Flash Point:149.8°C
PSA：125.04000
Density:2.043g/cm³
LogP:-0.25820
Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:8.4g/L(25 oC)
XLogP3:0
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:199.99570246
Heavy Atom Count:14
Complexity:387

Purity/Quality:

99% ^*data from raw suppliers

MeconicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(OC(=C(C1=O)O)C(=O)O)C(=O)O
Uses 3-hydroxy-4-oxopyran-2,6-dicarboxylic acid has anti inflammatory and antibacterial action. Meconic Acid has been used to detect the presence of opium . Meconic Acid has anti inflammatory and antibacterial action. Meconic Acid has been used to detect the presence of opium .

Technology Process of Meconic acid

There total 5 articles about Meconic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 3-benzyloxy-2,6-dicarboxy-γ-pyrone

: 497-59-6
meconic acid

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 70 ℃; for 4h; Inert atmosphere;
DOI:10.1080/00304948.2018.1525990

Reference yield: 30.0%

: 2029-49-4
2,6-dihydroxymethyl-3-hydroxy-4-pyrone

: 497-59-6
meconic acid

Guidance literature:: With sodium hydroxide; palladium on activated charcoal; air; for 144h; Ambient temperature;
DOI:10.1021/ja990402a

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 497-59-6
meconic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / aq. NaOH / methanol / 48 h

2: 30 percent / aq. NaOH, 10 percent Pd/C, air / 144 h / Ambient temperature

With sodium hydroxide; palladium on activated charcoal; air; In methanol;
DOI:10.1021/ja990402a