Stearanilide

Base Information

• Chemical Name: Stearanilide
• CAS No.: 637-54-7
• Molecular Formula: C24H41 N O
• Molecular Weight: 359.596
• Hs Code.: 2924299090
• European Community (EC) Number: 211-290-5
• DSSTox Substance ID: DTXSID6060921
• Nikkaji Number: J43.180J
• Wikidata: Q81989228
• Mol file: 637-54-7.mol

Synonyms:Stearanilide;637-54-7;N-phenyloctadecanamide;Octadecanamide, N-phenyl-;N-Phenylstearamide;Srearanilide;OCTADECANANILIDE;EINECS 211-290-5;C24H41NO;Stearinsaureanilid;N-Stearoylaniline;N-Phenylstearylamide;SCHEMBL2452465;DTXSID6060921;MFCD00048482;AKOS015839880;CS-0362561;FT-0632706;D92244;1-Benzyl-4-(hydroxymethyl)-1H-1,2,3-triazole

Chemical Property of Stearanilide

Chemical Property:

• Vapor Pressure: 2.62E-10mmHg at 25°C
• Melting Point: 94 °C
• Boiling Point: 154 °C / 10mmHg
• Flash Point: 313.9°C
• PSA: 29.10000
• Density: 0.93g/cm³
• LogP: 7.95960
• XLogP3: 9.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 17
• Exact Mass: 359.318814931
• Heavy Atom Count: 26
• Complexity: 309

Purity/Quality:

98%,99%, ^*data from raw suppliers

Stearanilide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NC1=CC=CC=C1

Technology Process of Stearanilide

There total 25 articles about Stearanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

stearic acid ethyl ester (111-61-5) + aniline (62-53-3) → N-phenylstearamide (637-54-7)

Guidance literature:

With indium (III) iodide; at 110 - 120 ℃; for 8h;

DOI:10.1081/SCC-120015715

Reference yield: 91.0%

→ N-phenylstearamide (637-54-7)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

In dichloromethane;

Reference yield: 32.0%

diphenylguanidine (102-06-7) + copper(II) stearate (660-60-6,7617-31-4,20563-00-2) → N-phenylstearamide (637-54-7)

Guidance literature:

With carbon monoxide; palladium dichloride; In benzonitrile; at 120 ℃; under 760.051 Torr;

DOI:10.1016/j.tet.2015.01.050

upstream raw materials:

stearic anhydride

aniline

phenyl isocyanate

stearic acid

Downstream raw materials:

N-(4-chlorophenyl)octadecanamide

N-(2-chlorophenyl) stearamide

C₃₉H₅₀N₂O₂

C₃₀H₄₆N₂

Refernces

• 1、 -. "A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE". Paragraph 0078-0084; 0135-0136. . Retrieved 2016/12/01.
• 2、 Hosseini-Sarvari, Mona,Sodagar, Esmat,Doroodmand, Mohammad Mahdi. "Nano sulfated titania as solid acid catalyst in direct synthesis of fatty acid amides". supporting information; experimental part. p. 2853 - 2859. Retrieved 2011/05/17.