4-Ethyl-4-phenylpiperidine

Base Information

• Chemical Name: 4-Ethyl-4-phenylpiperidine
• CAS No.: 58778-59-9
• Molecular Formula: C13H19 N
• Molecular Weight: 189.301
• European Community (EC) Number: 261-437-2
• UNII: TUF3R52CCR
• DSSTox Substance ID: DTXSID30207505
• Nikkaji Number: J297.028G
• Wikidata: Q83081421
• Mol file: 58778-59-9.mol

Synonyms:4-Ethyl-4-phenylpiperidine;58778-59-9;EINECS 261-437-2;TUF3R52CCR;4-ethyl-4-phenyl-piperidine;UNII-TUF3R52CCR;SCHEMBL3246807;DTXSID30207505;AKOS012457976;PIPERIDINE, 4-ETHYL-4-PHENYL-

Chemical Property of 4-Ethyl-4-phenylpiperidine

Chemical Property:

• Vapor Pressure: 0.00352mmHg at 25°C
• Boiling Point: 281.7°C at 760 mmHg
• Flash Point: 124.4°C
• PSA: 12.03000
• Density: 0.934g/cm³
• LogP: 3.04660
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 189.151749610
• Heavy Atom Count: 14
• Complexity: 164

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1(CCNCC1)C2=CC=CC=C2

Technology Process of 4-Ethyl-4-phenylpiperidine

There total 3 articles about 4-Ethyl-4-phenylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-ethyl-9-phenyl-3,7-diaza-bicyclo[3.3.1]nonane-2,4,6,8-tetraone (109407-86-5) → 4-ethyl-4-phenyl-piperidine (58778-59-9)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 250 ℃; under 183877 Torr; Hydrogenation;

DOI:10.1021/ja01548a030

Reference yield:

4-ethyl-1-benzyl-4-phenyl-piperidine; hydrochloride (109694-54-4) → 4-ethyl-4-phenyl-piperidine (58778-59-9)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;

DOI:10.1021/jo01362a043

Reference yield:

→ 4-ethyl-4-phenyl-piperidine (58778-59-9)

Guidance literature:

upstream raw materials:

9-ethyl-9-phenyl-3,7-diaza-bicyclo[3.3.1]nonane-2,4,6,8-tetraone

4-ethyl-1-benzyl-4-phenyl-piperidine; hydrochloride

Downstream raw materials:

4-ethyl-1-methyl-4-phenyl-piperidine