2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol

Base Information

Chemical Name:2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol
CAS No.:86758-97-6
Molecular Formula:C₂₅H₂₄ClN₃OS
Molecular Weight:450.004
Hs Code.:
Mol file:86758-97-6.mol

Synonyms:Dibenzo[b,f]thiepin,phenol deriv.

Suppliers and Price of 2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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American Custom Chemicals Corporation
2-(((4-(2-CHLORO-10,11-DIHYDRODIBENZO(B,F)THIEPIN-10-YL)-1-PIPERAZINYL)IMINO)METHYL)PHENOL 95.00%
5MG
$ 497.39

Total 0 raw suppliers

Chemical Property of 2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol

Chemical Property:

Vapor Pressure:2.38E-13mmHg at 25°C
Melting Point:195 - 197 °C (ethanol)
Boiling Point:577.8°C at 760 mmHg
Flash Point:303.3°C
PSA：64.37000
Density:1.37g/cm³
LogP:5.32150

Purity/Quality:: 2-(((4-(2-CHLORO-10,11-DIHYDRODIBENZO(B,F)THIEPIN-10-YL)-1-PIPERAZINYL)IMINO)METHYL)PHENOL 95.00% ^*data from reagent suppliers

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Technology Process of 2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol

There total 3 articles about 2-(((4-(2-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl )imino)methyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 86759-20-8
10-(4-aminopiperazino)-2-chloro-10,11-dihydrodibenzothiepin

: 90-02-8
salicylaldehyde

: 86758-97-6
2-{[(E)-4-(2-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-ylimino]-methyl}-phenol

Guidance literature:: In ethanol; for 0.25h; Heating;
DOI:10.1135/cccc19831173

Reference yield:

: 86759-17-3
2-chloro-10-(4-nitrosopiperazino)-10,11-dihydrodibenzothiepin

: 86758-97-6
2-{[(E)-4-(2-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-ylimino]-methyl}-phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / LiAlH₄ / diethyl ether / 5 h / Ambient temperature

2: 86 percent / ethanol / 0.25 h / Heating

With lithium aluminium tetrahydride; In diethyl ether; ethanol;
DOI:10.1135/cccc19831173

Reference yield:

: 52548-24-0
1-(2-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazine

: 86758-97-6
2-{[(E)-4-(2-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-ylimino]-methyl}-phenol

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / NaNO₂, aq. HCl / 1.) 75-80 deg C, 3 h, 2.) R_.T_., overnight.

2: 97 percent / LiAlH₄ / diethyl ether / 5 h / Ambient temperature

3: 86 percent / ethanol / 0.25 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; sodium nitrite; In diethyl ether; ethanol;
DOI:10.1135/cccc19831173