1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol

Base Information

Chemical Name:1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
CAS No.:5660-33-3
Molecular Formula:C17H13F3N2O2
Molecular Weight:334.2925
Hs Code.:
DSSTox Substance ID:DTXSID40386315
ChEMBL ID:CHEMBL1535597

Synonyms:1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol;5660-33-3;AC1MEPNB;MLS001197013;CHEMBL1535597;SCHEMBL16210992;DTXSID40386315;GCIZXSKDPAABMM-UHFFFAOYSA-N;HMS2879K05;CCG-18602;STK053863;AKOS001642468;SMR000555663;AB00092201-01;[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](phenyl)methanone

Suppliers and Price of 1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol

Chemical Property:

Vapor Pressure:3.1E-08mmHg at 25°C
Boiling Point:432.1°C at 760 mmHg
Flash Point:215.1°C
Density:1.33g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:334.09291215
Heavy Atom Count:24
Complexity:509

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=NN(C1(C(F)(F)F)O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol

There total 5 articles about 1-benzoyl-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: C₁₈H₁₅N₃O₃

: 5660-33-3
quinoxaline-2,3-dicarboximide

Guidance literature:: With Jones reagent; In acetone; at 20 ℃; for 1h;
DOI:10.1016/j.tet.2018.11.023

Reference yield: 79.0%

: 6924-99-8
Quinoxaline-2,3-dicarboxylic acid

: 5660-33-3
quinoxaline-2,3-dicarboximide

Guidance literature:: With ammonia; at 250 ℃; for 0.166667h;
DOI:10.1134/S1070428007070226

Reference yield:

: C₁₈H₁₇N₃O₂

: 5660-33-3
quinoxaline-2,3-dicarboximide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; potassium peroxymonosulfate sulfate / dimethyl sulfoxide / 1.5 h / 80 °C

2: Jones reagent / acetone / 1 h / 20 °C

With copper(l) iodide; Jones reagent; potassium peroxymonosulfate sulfate; In dimethyl sulfoxide; acetone;
DOI:10.1016/j.tet.2018.11.023