N-[(3-methoxyphenyl)methylidene]hydroxylamine

Base Information

• Chemical Name: N-[(3-methoxyphenyl)methylidene]hydroxylamine
• CAS No.: 38489-80-4
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.165
• Hs Code.: 2928000090
• European Community (EC) Number: 692-347-5
• DSSTox Substance ID: DTXSID80959360
• Mol file: 38489-80-4.mol

Synonyms:3-Methoxybenzaldehyde oxime;38489-80-4;N-[(3-methoxyphenyl)methylidene]hydroxylamine;3-anisaldoxime;DTXSID80959360;VDCBJAPSEUTPTQ-UHFFFAOYSA-N;AKOS017263822;FT-0682795

Chemical Property of N-[(3-methoxyphenyl)methylidene]hydroxylamine

Chemical Property:

• Vapor Pressure: 0.00731mmHg at 25°C
• Boiling Point: 257.8°Cat760mmHg
• Flash Point: 109.7°C
• PSA: 41.82000
• Density: 1.07g/cm³
• LogP: 1.50330
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 151.063328530
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

98%min ^*data from raw suppliers

3-Methoxy-benzaldehydeoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C=NO

Technology Process of N-[(3-methoxyphenyl)methylidene]hydroxylamine

There total 18 articles about N-[(3-methoxyphenyl)methylidene]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-methoxy-benzaldehyde (591-31-1) → (E)-3-methoxybenzaldoxime (38489-80-4,52707-57-0,52707-52-5)

Guidance literature:

With perchloric acid; ethyl acetohydroximate; In dichloromethane; water; at 20 ℃; for 24h; Reagent/catalyst; Solvent; Catalytic behavior; Inert atmosphere;

Reference yield: 97.0%

3-methoxy-benzaldehyde (591-31-1) → 3-methoxybenzaldehyde oxime (38489-80-4)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In ethanol; at 20 ℃;

DOI:10.1021/acs.oprd.8b00113

Reference yield: 94.0%

3-METHOXYBENZYLAMINE (5071-96-5) → (E)-3-methoxybenzaldoxime (38489-80-4,52707-57-0,52707-52-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In ethyl acetate; at 20 ℃; for 0.333333h;

DOI:10.1021/acs.joc.5b01740

upstream raw materials:

3-methoxy-benzaldehyde

hexahydro-1,3,5-tris-(3-methoxyphenyl)-1,3,5-triazine

m-Anisidine

methoxybenzene

Downstream raw materials:

3-methoxybenzonitrile

3-METHOXYBENZYLAMINE

benzoic acid-(3-methoxy-benzylidenehydrazide)

Acetic acid (2R,3R,4S,6S)-3,5-diacetoxy-2-acetoxymethyl-6-(2-chloro-N-hydroxy-5-methoxy-benzimidoylsulfanyl)-tetrahydro-pyran-4-yl ester

Refernces

• 1、 Hsueh, Nai-Chen,Chen, Shin-Mei,Lin, Chun-Yi,Chang, Meng-Yang. "HCl-mediated cascade cyclocondensation of oxygenated arylacetic acids with arylaldehydes: one-pot synthesis of 1-arylisoquinolines". . p. 1047 - 1059. Retrieved 2021/02/16.
• 2、 Granato, álisson Silva,de Carvalho, Gustavo S. Gon?alves,Fonseca, Carla G.,Adrio, Javier,Leit?o, Alexandre A.,Amarante, Giovanni Wilson. "On the mixed oxides-supported niobium catalyst towards benzylamine oxidation". . p. 118 - 125. Retrieved 2020/09/11.