[2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 4-methylbenzenesulfonate

Base Information

• Chemical Name: [2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 4-methylbenzenesulfonate
• CAS No.: 32953-63-2
• Molecular Formula: C₁₇H₂₀O₈S₂
• Molecular Weight: 416.473
• NSC Number: 185302
• DSSTox Substance ID: DTXSID60307002

Synonyms:32953-63-2;NSC185302;DTXSID60307002;NSC-185302;2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydro-2H-furo[2,3-d][1,3]dioxol-6-yl 4-methylbenzene-1-sulfonate (non-preferred name)

Chemical Property of [2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 4-methylbenzenesulfonate

Chemical Property:

• Vapor Pressure: 3.08E-12mmHg at 25°C
• Boiling Point: 552.2°Cat760mmHg
• Flash Point: 287.7°C
• Density: 1.49g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 416.05995994
• Heavy Atom Count: 27
• Complexity: 680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC2C(OC3C2OC(O3)(C)C)C4CSC(=O)O4

Technology Process of [2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 4-methylbenzenesulfonate

There total 8 articles about [2,2-Dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl] 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.2%

1,2-O-Isopropyliden-3-O-p-toluolsulfonyl-α-D-glucofuranose-5,6-thionocarbonat (2872-64-2) → 5-deoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-xylo-hexofuranose (62102-11-8) + Toluene-4-sulfonic acid (3aR,5R,6S,6aR)-2,2-dimethyl-5-((S)-2-oxo-[1,3]oxathiolan-5-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester (32953-63-2) + (R)-4-((3aR,5S,6R,6aR)-6-Hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-[1,3]oxathiolan-2-one + Toluene-4-sulfonic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-((R)-2-oxo-[1,3]oxathiolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Guidance literature:

With bis(tri-n-butyltin); In benzene; at 10 - 15 ℃; for 4h; Further byproducts given; Irradiation;

Reference yield: 14.2%

1,2-O-Isopropyliden-3-O-p-toluolsulfonyl-α-D-glucofuranose-5,6-thionocarbonat (2872-64-2) → Toluene-4-sulfonic acid (3aR,5R,6S,6aR)-2,2-dimethyl-5-((S)-2-oxo-[1,3]oxathiolan-5-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester (32953-63-2) + (R)-4-((3aR,5S,6R,6aR)-6-Hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-[1,3]oxathiolan-2-one + (S)-5-((3aR,5S,6S,6aR)-6-Hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-[1,3]oxathiolan-2-one + Toluene-4-sulfonic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-((R)-2-oxo-[1,3]oxathiolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Guidance literature:

With bis(tri-n-butyltin); In benzene; at 10 - 15 ℃; for 4h; Further byproducts given; Irradiation;

Reference yield: 14.2%

1,2-O-Isopropyliden-3-O-p-toluolsulfonyl-α-D-glucofuranose-5,6-thionocarbonat (2872-64-2) → Toluene-4-sulfonic acid (3aR,5R,6S,6aR)-2,2-dimethyl-5-((S)-2-oxo-[1,3]oxathiolan-5-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester (32953-63-2) + (R)-4-((3aR,5S,6R,6aR)-6-Hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-[1,3]oxathiolan-2-one + Toluene-4-sulfonic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-((S)-2-oxo-[1,3]oxathiolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester + Toluene-4-sulfonic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-((R)-2-oxo-[1,3]oxathiolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Guidance literature:

With bis(tri-n-butyltin); In benzene; at 10 - 15 ℃; for 4h; Further byproducts given; Irradiation;

upstream raw materials:

1,2-O-Isopropyliden-3-O-p-toluolsulfonyl-α-D-glucofuranose-5,6-thionocarbonat

1,2-di-O-isopropylidene-5,6-O-thiocarbonyl-α-D-glucofuranose

1,2-O-isopropylidene-α-D-glucofuranose

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 32953-63-2 2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl 4-methylbenzenesulfonate (non-preferred name)

Send

Send

Metric Ton KG G Pound L ML

Send

Send