N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid

Base Information

Chemical Name:N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid
CAS No.:2820-44-2
Molecular Formula:C₁₃H₁₄N₂O₆
Molecular Weight:294.264
Hs Code.:
DSSTox Substance ID:DTXSID90946286
Mol file:2820-44-2.mol

Synonyms:N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid;2353-39-1;4-(o-Carboxybenzamido)glutaramic acid;4-(o-Carboxybenzamido) glutaramic acid;Phthalamic acid, N-(1-carbamoyl-3-carboxypropyl)-;SCHEMBL10023117;DTXSID90946286;Benzoic acid, 2-[[[1-(aminocarbonyl)-3-carboxypropyl]amino]carbonyl]-;2-{[(4-Carboxy-1-hydroxy-1-iminobutan-2-yl)imino](hydroxy)methyl}benzoic acid

Suppliers and Price of N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid

Chemical Property:

Vapor Pressure:4.98E-21mmHg at 25°C
Boiling Point:707.8°Cat760mmHg
Flash Point:381.9°C
Density:1.441g/cm³
XLogP3:-0.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:294.08518617
Heavy Atom Count:21
Complexity:436

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC(CCC(=O)O)C(=O)N)C(=O)O

Technology Process of N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid

There total 3 articles about N-(1-Carbamoyl-3-carboxypropyl)phthalamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: N-(2-(benzyloxycarbonyl)benzoyl)isoglutamine benzyl ester

: 2353-39-1,2820-44-2,30076-84-7
N-(o-Carboxybenzoyl)-D,L-isoglutamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In 1,4-dioxane; at 20 ℃; for 2h;
DOI:10.1248/cpb.55.651

Reference yield:

: 18800-75-4,63091-89-4
H-Glu(OBn)-NH₂ hydrochloride

: 2353-39-1,2820-44-2,30076-84-7
N-(o-Carboxybenzoyl)-D,L-isoglutamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: methyl chloroformate; Et₃N / tetrahydrofuran / 0.5 h / 0 °C

1.2: 46 percent / tetrahydrofuran / 3 h / 0 - 20 °C

2.1: 98 percent / H₂ / Pd/C / dioxane / 2 h / 20 °C

With hydrogen; triethylamine; methyl chloroformate; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1248/cpb.55.651

Reference yield:

: 2528-16-7
o-(benzyloxycarbonyl)benzoic acid

: 2353-39-1,2820-44-2,30076-84-7
N-(o-Carboxybenzoyl)-D,L-isoglutamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: methyl chloroformate; Et₃N / tetrahydrofuran / 0.5 h / 0 °C

1.2: 46 percent / tetrahydrofuran / 3 h / 0 - 20 °C

2.1: 98 percent / H₂ / Pd/C / dioxane / 2 h / 20 °C

With hydrogen; triethylamine; methyl chloroformate; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1248/cpb.55.651