(S)-(-)-2-Methoxypropionamide

Base Information

• Chemical Name: (S)-(-)-2-Methoxypropionamide
• CAS No.: 336111-20-7
• Molecular Formula: C₄H₉NO₂
• Molecular Weight: 103.121
• DSSTox Substance ID: DTXSID80955246
• Nikkaji Number: J53.584B
• Wikidata: Q82934750
• Mol file: 336111-20-7.mol

Synonyms:(S)-(-)-2-METHOXYPROPIONAMIDE;(2S)-2-methoxypropanamide;336111-20-7;(S)-2-methoxypropanamide;2-Methoxypropanimidic acid;(S)-2-Methoxypropionamide;SCHEMBL1469539;DTXSID80955246;WOGXHNJBKGZMHV-VKHMYHEASA-N;AKOS006278693;J-019270

Chemical Property of (S)-(-)-2-Methoxypropionamide

Chemical Property:

• Vapor Pressure: 0.252mmHg at 25°C
• Melting Point: 76-78oC
• Refractive Index: 1.4183 (estimate)
• Boiling Point: 205.3°Cat760mmHg
• Flash Point: 105.4°C
• PSA: 52.32000
• Density: 1.01g/cm³
• LogP: 0.20690
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 103.063328530
• Heavy Atom Count: 7
• Complexity: 72.1

Purity/Quality:

(S)-(-)-2-Methoxypropionamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)N)OC
• Isomeric SMILES: C[C@@H](C(=O)N)OC
• Uses: (S)-(-)-2-Methoxypropionamide (cas# 336111-20-7) is a compound useful in organic synthesis.

Technology Process of (S)-(-)-2-Methoxypropionamide

There total 5 articles about (S)-(-)-2-Methoxypropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-methoxypropionate (17639-76-8,92935-45-0) → 2-methoxy-propionic acid amide (22543-21-1,336111-21-8,336111-20-7)

Guidance literature:

With methanol; ammonia; at 0 ℃;

DOI:10.1039/jr9340001722

Reference yield:

R-(+)-2-methoxypropionic acid chloride (61915-18-2) → (R)-(+)-2-methoxypropionamide (22543-21-1,336111-21-8,336111-20-7)

Guidance literature:

With ammonia; benzene; at 0 ℃;

Reference yield:

2-methoxy-propanenitrile (33695-59-9) → 2-methoxy-propionic acid amide (22543-21-1,336111-21-8,336111-20-7)

Guidance literature:

With water; borax buffer; at 80 ℃; Rate constant; Mechanism;

upstream raw materials:

2-methoxy-propanenitrile

methyl 2-methoxypropionate

ethyl 2-methoxypropionate

Methyl 2-bromopropionate

Downstream raw materials:

ammonia

acetaldehyde