3-Cyano-6-methyl-2(1H)-pyridinone

Base Information Edit

Chemical Name:3-Cyano-6-methyl-2(1H)-pyridinone
CAS No.:4241-27-4
Deprecated CAS:39215-39-9
Molecular Formula:C7H6 N2 O
Molecular Weight:134.137
Hs Code.:2933399090
European Community (EC) Number:224-202-5
NSC Number:15124
DSSTox Substance ID:DTXSID4063375
Nikkaji Number:J101.140E
Wikidata:Q72458614
ChEMBL ID:CHEMBL1275951
Mol file:4241-27-4.mol

Synonyms:4241-27-4;2-hydroxy-6-methylnicotinonitrile;3-Cyano-6-methyl-2(1H)-pyridinone;3-Cyano-6-methyl-2-pyridone;6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile;2-Hydroxy-6-methyl-nicotinonitrile;6-methyl-2-oxo-1H-pyridine-3-carbonitrile;2-hydroxy-6-methylpyridine-3-carbonitrile;3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-2-oxo-;3-Cyano-2-hydroxy-6-methylpyridine;NSC 15124;Nicotinonitrile, 1,2-dihydro-6-methyl-2-oxo-;EINECS 224-202-5;1,2-Dihydro-6-methyl-2-oxonicotinonitrile;6-Methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile;MFCD00084984;3-Cyano-6-methyl-2(1)-pyridone;NSC15124;MFCD00006013;6-Methyl-3-cyanopyridin-2ol;1,2-Dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile;3-Cyano-6-methyl-2-pyridinol;5-Cyano-6-hydroxy-2-picoline;SCHEMBL1145328;CHEMBL1275951;DTXSID4063375;HMS1693D08;CS-M1410;2-hydroxy-3-cyano-6-methylpyridine;3-Cyano-6-methyl-2(1H)pyridinone;3-cyano-6-methylpyridin-2(1h)-one;NSC-15124;STK363118;STL365543;TD8121;AKOS000164247;AKOS000417364;AC-6356;AS-5402;FG-0431;PB32084;SY003427;Nicotinonitrile,2-dihydro-6-methyl-2-oxo-;2-keto-6-methyl-1H-pyridine-3-carbonitrile;3-Cyano-6-methyl-2(1H)-pyridinone, 97%;A6928;AM20051174;C2210;FT-0615547;EN300-24211;3-Pyridinecarbonitrile,2-dihydro-6-methyl-2-oxo-;AE-842/30162007;Q-101978;6-Methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile #;Z169914018;2-Hydroxy-6-methylnicotinonitrile

Suppliers and Price of 3-Cyano-6-methyl-2(1H)-pyridinone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Cyano-6-methyl-2(1H)-pyridinone
10g
$ 100.00

TCI Chemical
3-Cyano-6-methyl-2-pyridone >98.0%(T)
5g
$ 54.00

TCI Chemical
3-Cyano-6-methyl-2-pyridone >98.0%(T)
25g
$ 166.00

SynQuest Laboratories
6-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
50 g
$ 206.00

SynQuest Laboratories
6-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
5 g
$ 40.00

SynQuest Laboratories
6-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
10 g
$ 60.00

Sigma-Aldrich
3-Cyano-6-methyl-2(1H)-pyridinone 97%
5g
$ 57.50

Oakwood
3-Cyano-6-methyl-2-pyridone 98%
1g
$ 10.00

Oakwood
3-Cyano-6-methyl-2-pyridone 98%
5g
$ 27.00

Matrix Scientific
2-Hydroxy-6-methylnicotinonitrile 95%+
1g
$ 567.00

Total 82 raw suppliers

Chemical Property of 3-Cyano-6-methyl-2(1H)-pyridinone Edit

Chemical Property:

Appearance/Colour:SLIGHTLY YELLOW GRANULAR CRYSTALLINE POWDER
Vapor Pressure:0.00118mmHg at 25°C
Melting Point:293-295 ºC
Refractive Index:1.5880 (estimate)
Boiling Point:341.4 °C at 760 mmHg
PKA:9.03±0.10(Predicted)
Flash Point:160.3 °C
PSA：56.65000
Density:1.2 g/cm³
LogP:0.55498
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:2.38 g/L (20 ºC)
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:134.048012819
Heavy Atom Count:10
Complexity:277

Purity/Quality:

99% ^*data from raw suppliers

3-Cyano-6-methyl-2(1H)-pyridinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn,Xi
Statements: 36/37/38-20/21/22
Safety Statements: 36/37/39-26-22-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC=C(C(=O)N1)C#N
Uses 3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3?-pyridyl thiamine, a potent in vitro thiamine antagonist.

Technology Process of 3-Cyano-6-methyl-2(1H)-pyridinone

There total 23 articles about 3-Cyano-6-methyl-2(1H)-pyridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%