Pacodine

Base Information

• Chemical Name: Pacodine
• CAS No.: 18783-43-2
• Molecular Formula: C₁₉H₁₉NO₄
• Molecular Weight: 325.364
• Mol file: 18783-43-2.mol

Synonyms:

Chemical Property of Pacodine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pacodine

There total 3 articles about Pacodine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-<3',4'-dimethoxybenzyl>-7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline (57606-03-8) → pacodine (18783-43-2)

Guidance literature:

With palladium; at 175 ℃; under 10 Torr;

DOI:10.1007/BF00903594

Reference yield:

6-methoxy-1-veratryl-3,4-dihydro-isoquinolin-7-ol; hydrochloride → pacodine (18783-43-2)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; water / Hydrogenation

2: palladium / 175 °C / 10 Torr

With water; palladium; platinum;

DOI:10.1007/BF00903594

Reference yield:

→ pacodine (18783-43-2)

Guidance literature:

1-(3,4-Dimethoxybenzyl)-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline X/Tetralin, H2-Pd-charcoal;

DOI:10.1002/jps.2600571120

upstream raw materials:

1-<3',4'-dimethoxybenzyl>-7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline