bis(3-bromo-4-hydroxy-phenyl)methanone

Base Information

• Chemical Name: bis(3-bromo-4-hydroxy-phenyl)methanone
• CAS No.: 5423-21-2
• Molecular Formula: C13H8 Br2 O3
• Molecular Weight: 372.01
• Hs Code.: 2914700090
• Mol file: 5423-21-2.mol

Synonyms:Benzophenone,3,3'-dibromo-4,4'-dihydroxy- (8CI); NSC 4517

Chemical Property of bis(3-bromo-4-hydroxy-phenyl)methanone

Chemical Property:

• Vapor Pressure: 5.81E-10mmHg at 25°C
• Boiling Point: 483.2°Cat760mmHg
• Flash Point: 246°C
• PSA: 57.53000
• Density: 1.89g/cm³
• LogP: 3.85380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bis(3-bromo-4-hydroxy-phenyl)methanone

There total 7 articles about bis(3-bromo-4-hydroxy-phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

bis(3-bromo-4-methoxyphenyl)methanone (79616-15-2) → 4,4'-dihydroxy-3,3'-dibromobenzophenone (5423-21-2)

Guidance literature:

With pyridine hydrochloride; at 210 ℃; for 0.333333h;

Reference yield:

4,4'-didodecyloxy-3,3'-dibromobenzophenone → 4,4'-dihydroxy-3,3'-dibromobenzophenone (5423-21-2)

Guidance literature:

With aluminum (III) chloride; In chloroform; at 20 ℃; for 4h; Cooling with ice;

Reference yield:

bis(p-methoxyphenyl)methanone (90-96-0) → 4,4'-dihydroxy-3,3'-dibromobenzophenone (5423-21-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 77.8 percent / Br₂ / acetic acid / 1 h

2: 85 percent / pyridine*HCl / 0.33 h / 210 °C

With bromine; pyridine hydrochloride; In acetic acid;

upstream raw materials:

bis(3-bromo-4-methoxyphenyl)methanone

bis(p-methoxyphenyl)methanone

1,1-dichloro-2,2-bis(p-methoxyphenyl)ethylene

Methoxychlor

Refernces

• 1、 Lesiak, T.,Nowakowski, J.. "Applying of 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane for the Synthesis of Diphenols". . p. 684 - 690. Retrieved 2007/10/02.