8-Quinolinamine, N-(2-((2-aminoethyl)thio)propyl)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-

Base Information

• Chemical Name: 8-Quinolinamine, N-(2-((2-aminoethyl)thio)propyl)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-
• CAS No.: 98586-87-9
• Molecular Formula: C₂₃H₂₆F₃N₃O₂S
• Molecular Weight: 465.54
• DSSTox Substance ID: DTXSID50913176
• ChEMBL ID: CHEMBL302679
• Mol file: 98586-87-9.mol

Synonyms:8-((5'-amino-2'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinoline;8-((5'-amino-2'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinoline fumarate;8-ATMTPQ

Chemical Property of 8-Quinolinamine, N-(2-((2-aminoethyl)thio)propyl)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-

Chemical Property:

• Vapor Pressure: 7.86E-14mmHg at 25°C
• Boiling Point: 588.6°Cat760mmHg
• Flash Point: 309.7°C
• PSA: 94.70000
• Density: 1.276g/cm³
• LogP: 6.62850
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 9
• Exact Mass: 465.16978274
• Heavy Atom Count: 32
• Complexity: 571

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C2C(=C(C=C(C2=NC=C1)NCC(C)SCCN)OC)OC3=CC=CC(=C3)C(F)(F)F

Technology Process of 8-Quinolinamine, N-(2-((2-aminoethyl)thio)propyl)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-

There total 1 articles about 8-Quinolinamine, N-(2-((2-aminoethyl)thio)propyl)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methoxy-4-methyl-8-<(2'-methyl-5'-phthalimido-3'-thiapentyl)amino>-5-quinoline (98586-93-7) → 8-[(5'-amino-2'-methyl-3'-thiapentyl)amino]-6-methoxy-4-methyl-5-[m-(trifluoromethyl)phenoxy]quinoline (98586-87-9)

Guidance literature:

With hydrazine; In ethanol; for 2h; Heating;

DOI:10.1021/jm00150a035

upstream raw materials:

6-methoxy-4-methyl-8-<(2'-methyl-5'-phthalimido-3'-thiapentyl)amino>-5-quinoline