3-(3,4-Dimethoxyphenethyl)-2-thioxo-4-thiazolidinone

Base Information

• Chemical Name: 3-(3,4-Dimethoxyphenethyl)-2-thioxo-4-thiazolidinone
• CAS No.: 23522-20-5
• Molecular Formula: C₁₃H₁₅NO₃S₂
• Molecular Weight: 297.399
• Hs Code.: 2934999090
• Mol file: 23522-20-5.mol

Synonyms:Rhodanine,3-(3,4-dimethoxyphenethyl)- (8CI); NSC 150548

Chemical Property of 3-(3,4-Dimethoxyphenethyl)-2-thioxo-4-thiazolidinone

Chemical Property:

• Vapor Pressure: 1.35E-07mmHg at 25°C
• Boiling Point: 429.9°Cat760mmHg
• Flash Point: 213.8°C
• PSA: 96.16000
• Density: 1.34g/cm³
• LogP: 2.04450

Purity/Quality:

99% ^*data from raw suppliers

3-(3,4-DIMETHOXYPHENETHYL)-RHODANINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-[2-(3,4-Dimethoxyphenyl)ethyl]-2-sulfanylidene-1,3-thiazolidin-4-one is used in preparation of arylmethylene and heterocyclylmethylene thiazolidinediones and analogs as tumor necrosis factor inhibitors.

Technology Process of 3-(3,4-Dimethoxyphenethyl)-2-thioxo-4-thiazolidinone

There total 2 articles about 3-(3,4-Dimethoxyphenethyl)-2-thioxo-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

→ 3-(3,4-dimethoxy-phenethyl)-2-thioxo-thiazolidin-4-one (23522-20-5)

Guidance literature:

Reference yield:

potassium chloroacetate (7748-25-6) → 3-(3,4-dimethoxy-phenethyl)-2-thioxo-thiazolidin-4-one (23522-20-5)

Guidance literature:

With acetic acid;

DOI:10.1021/ja01358a034

upstream raw materials:

potassium chloroacetate

Refernces