(15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2

Base Information

Chemical Name:(15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2
CAS No.:85235-20-7
Molecular Formula:C21H32O4
Molecular Weight:348.4764
Hs Code.:
UNII:0228OHS8XE

Synonyms:15-Methyl-delta(sup 9)-pgd2;BRN 5987971;(15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2;0228OHS8XE;UNII-0228OHS8XE;Prosta-5,9,13-trien-1-oic acid, 15-hydroxy-15-methyl-11-oxo-, (5Z,9-alpha,13E,15S)-;(15S)-15-Methyl-9-deoxy-delta(sup 9)-prostaglandin D2;85235-20-7;15-Methyl-9-deoxy-delta(sup 9)prostaglandin D2, (15S)-;LS-125849;15-METHYL-9-DEOXY-.DELTA.(SUP 9)PROSTAGLANDIN D2, (15S)-;15-HYDROXY-15-METHYL-11-OXO-PROSTA-5,9,13-TRIEN-1-OIC ACID, (5Z,13E,15S)-;PROSTA-5,9,13-TRIEN-1-OIC ACID, 15-HYDROXY-15-METHYL-11-OXO-, (5Z,13E,15S)-

Suppliers and Price of (15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2

Chemical Property:

Vapor Pressure:2.62E-13mmHg at 25°C
Boiling Point:527°Cat760mmHg
Flash Point:286.6°C
PSA：74.60000
Density:1.091g/cm³
LogP:4.44640
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:12
Exact Mass:348.23005950
Heavy Atom Count:25
Complexity:518

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(C)(C=CC1C(C=CC1=O)CC=CCCCC(=O)O)O
Isomeric SMILES:CCCCC[C@@](C)(/C=C/[C@@H]1[C@H](C=CC1=O)C/C=C\CCCC(=O)O)O

Technology Process of (15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2

There total 3 articles about (15S)-15-Methyl-9-deoxy-delta(sup 9)-pgd2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85235-19-4
(Z)-(1R,3aS,11aR)-1-((E)-(S)-3-Hydroxy-3-methyl-oct-1-enyl)-1,3,3a,6,7,8,11,11a-octahydro-4-oxa-cyclopentacyclodecene-2,5-dione

: 85235-20-7
(15S)-15-methyl-9-deoxy-Δ⁹-PGD₂

Guidance literature:: With silica gel; In methanol; ethyl acetate;
DOI:10.1021/jm00360a003

Reference yield:

: 35700-23-3
Carboprost

: 85235-20-7
(15S)-15-methyl-9-deoxy-Δ⁹-PGD₂

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / 2,2'-dipyridyl disulfide, PPh₃ / xylene / a) 25 deg C, 18 h, b) reflux, 4 h

2: 440 mg / H₂CrO₄, H₂SO₄ / acetone / a) -40 deg C, 2 h, b) -30 deg C, 1.5 h

3: 190 mg / silica gel / ethyl acetate; methanol

With 2,2'-dipyridyldisulphide; sulfuric acid; silica gel; chromic acid; triphenylphosphine; In methanol; ethyl acetate; acetone; xylene;
DOI:10.1021/jm00360a003

Reference yield:

: 62411-08-9
(15S)-15-methyl-PGF_2α 1,9-lactone

: 85235-20-7
(15S)-15-methyl-9-deoxy-Δ⁹-PGD₂

Guidance literature:: Multi-step reaction with 2 steps

1: 440 mg / H₂CrO₄, H₂SO₄ / acetone / a) -40 deg C, 2 h, b) -30 deg C, 1.5 h

2: 190 mg / silica gel / ethyl acetate; methanol

With sulfuric acid; silica gel; chromic acid; In methanol; ethyl acetate; acetone;
DOI:10.1021/jm00360a003