6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-

Base Information

Chemical Name:6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-
CAS No.:98234-97-0
Molecular Formula:C12H11N3O2
Molecular Weight:229.2346
Hs Code.:
DSSTox Substance ID:DTXSID70243523
Wikidata:Q83127619

Synonyms:5,11-Dihydro-6H-1,3-dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine;6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-;98234-97-0;SCHEMBL7333039;DTXSID70243523;LEPAVKIGHTXSIB-UHFFFAOYSA-N;LS-62691;7,8-methylenedioxy-10,11-dihydro-5H-imidazo-[2,1-c][1,4]benzodiazepine;7,8-methylenedioxy-10,11-dihydro-5H-imidazo[2,1-c][1,4]benzodiazepine

Suppliers and Price of 6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-

Chemical Property:

Vapor Pressure:2.51E-10mmHg at 25°C
Boiling Point:505.1°Cat760mmHg
Flash Point:259.3°C
Density:1.58g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:229.085126602
Heavy Atom Count:17
Complexity:302

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=NC=CN2CC3=CC4=C(C=C3N1)OCO4

Technology Process of 6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro-

There total 5 articles about 6H-1,3-Dioxolo(4,5-h)imidazo(2,1-c)(1,4)benzodiazepine, 5,11-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.2%

: 98234-94-7
C₁₂H₉N₃O₂

: 98234-97-0
7,8-methylenedioxy-10,11-dihydro-5H-imidazo-[2,1-c][1,4]benzodiazepine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 50 ℃; for 5h; under 3040 Torr;

Reference yield:

: 15862-98-3
5-(chloromethyl)-6-nitrobenzo[d][1,3]dioxole

: 98234-97-0
7,8-methylenedioxy-10,11-dihydro-5H-imidazo-[2,1-c][1,4]benzodiazepine

Guidance literature:: Multi-step reaction with 5 steps

1: 38.4 percent / Na₂CO₃ / dimethylformamide / 3 h / 125 °C

2: 39.1 percent / H₂O / 115 °C / sealed tube, overnight

3: 90.6 percent / activated MnO₂ / acetone / Ambient temperature

4: 88.2 percent / iron(II) sulphate heptahydrate, NH₄OH 32percent / ethanol; H₂O / 1 h / 120 °C

5: 87.2 percent / H₂ / 10percent Pd/C / ethyl acetate / 5 h / 50 °C / 3040 Torr

With manganese(IV) oxide; ammonium hydroxide; hydrogen; sodium carbonate; iron(II) sulfate; palladium on activated charcoal; In ethanol; water; ethyl acetate; N,N-dimethyl-formamide; acetone;

Reference yield:

: 98235-00-8
1-(6-Nitro-benzo[1,3]dioxol-5-ylmethyl)-1H-imidazole

: 98234-97-0
7,8-methylenedioxy-10,11-dihydro-5H-imidazo-[2,1-c][1,4]benzodiazepine

Guidance literature:: Multi-step reaction with 4 steps

1: 39.1 percent / H₂O / 115 °C / sealed tube, overnight

2: 90.6 percent / activated MnO₂ / acetone / Ambient temperature

3: 88.2 percent / iron(II) sulphate heptahydrate, NH₄OH 32percent / ethanol; H₂O / 1 h / 120 °C

4: 87.2 percent / H₂ / 10percent Pd/C / ethyl acetate / 5 h / 50 °C / 3040 Torr

With manganese(IV) oxide; ammonium hydroxide; hydrogen; iron(II) sulfate; palladium on activated charcoal; In ethanol; water; ethyl acetate; acetone;