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Technology Process of (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone

(6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone

Base Information
  • Chemical Name:(6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone
  • CAS No.:164178-33-0
  • Molecular Formula:C23H25IN2O3
  • Molecular Weight:504.368
  • Hs Code.:
  • European Community (EC) Number:803-134-5
  • UNII:U1LNJ6NBKA
  • ChEMBL ID:CHEMBL181633
  • DSSTox Substance ID:DTXSID10167719
  • Nikkaji Number:J662.571A
  • Pharos Ligand ID:G779D7KZQTWM
  • Wikidata:Q4652499
  • Wikipedia:AM-630
  • Mol file:164178-33-0.mol
(6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone

Synonyms:1-(2-(morpholin-4-yl)ethyl)-2-methyl-3-(4-methoxybenzoyl)-6-iodoindole;2-methyl-3-(4-methoxybenzoyl)-6-iodo-1-(2-morpholinoethyl)-1H-indole;6-iodopravadoline;AM 630;AM-630;AM630;iodopravadoline;methanone, (6-iodo-2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)(4-methoxyphenyl)-

Suppliers and Price of (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • AM 630
  • 10mg
  • $ 480.00
  • TRC
  • AM630
  • 100mg
  • $ 960.00
  • Tocris
  • AM630 ≥98%(HPLC)
  • 10
  • $ 227.00
  • Tocris
  • AM630 ≥98%(HPLC)
  • 50
  • $ 952.00
  • Sigma-Aldrich
  • AM630 ≥90% (HPLC)
  • 25mg
  • $ 528.00
  • Sigma-Aldrich
  • AM630 ≥90% (HPLC)
  • 5mg
  • $ 132.00
  • Matrix Scientific
  • (6-Iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone 95+%
  • 50mg
  • $ 247.00
  • DC Chemicals
  • Iodopravadoline(AM-630) >98%
  • 100 mg
  • $ 450.00
  • Crysdot
  • AM630 98+%
  • 100mg
  • $ 376.00
  • Crysdot
  • AM630 98+%
  • 50mg
  • $ 218.00
Total 44 raw suppliers
Chemical Property of (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone
Chemical Property:
  • Appearance/Colour:Off-white solid. 
  • Vapor Pressure:1.25E-14mmHg at 25°C 
  • Refractive Index:1.646 
  • Boiling Point:605.928 °C at 760 mmHg 
  • PKA:6.98±0.10(Predicted) 
  • Flash Point:320.254 °C 
  • PSA：43.70000 
  • Density:1.5 g/cm3 
  • LogP:4.06400 
  • Storage Temp.:Desiccate at +4°C 
  • Solubility.:DMSO: >5mg/mL 
  • XLogP3:4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:6
  • Exact Mass:504.09099
  • Heavy Atom Count:29
  • Complexity:548
Purity/Quality:

99%, *data from raw suppliers

AM 630 *data from reagent suppliers

Safty Information:
  • Pictogram(s): N 
  • Hazard Codes:N 
  • Statements: 50 
  • Safety Statements: 61 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=C(C2=C(N1CCN3CCOCC3)C=C(C=C2)I)C(=O)C4=CC=C(C=C4)OC
  • Uses AM 630 acts as a potential CB2 receptor cannabinoid antagonist with application towards human lung cancer treatment and angiogenesis induction. AM630 has been used: as a cannabinoid 2(CB2) inhibitor to study the analgesic effect exerted by polysaccharopeptide from?Trametes versicolor (TPSP).as a CB2 antagonist along with β-caryophyllene (BCP) to study its effects on re-epithilialization of fibroblast cells.as a CB2 antagonist to study its interaction with 17-β-estradiol in primary human osteoblasts.
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