Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Base Information

Chemical Name:Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-
CAS No.:75902-75-9
Molecular Formula:C₂₀H₃₁N₃O₅
Molecular Weight:393.483
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40226823
Nikkaji Number:J87.662C
Wikidata:Q83106367
ChEMBL ID:CHEMBL46807
Mol file:75902-75-9.mol

Synonyms:BRN 5155313;75902-75-9;Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-;N-(4,7-Dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-N'-methylurea;CHEMBL46807;DTXSID40226823;LS-159889;1-[4,7-Dimethoxy-6-[2-(dipropylamino)ethoxy]benzofuran-5-yl]-3-methylurea

Suppliers and Price of Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Chemical Property:

Vapor Pressure:2.94E-10mmHg at 25°C
Boiling Point:503.3°C at 760 mmHg
Flash Point:258.2°C
PSA：88.69000
Density:1.147g/cm³
LogP:3.97950
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:393.22637110
Heavy Atom Count:28
Complexity:461

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC)CCOC1=C(C2=C(C=CO2)C(=C1NC(=O)NC)OC)OC

Technology Process of Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl-

There total 5 articles about Urea, 1-(4,7-dimethoxy-6-(2-(dipropylamino)ethoxy)-5-benzofuranyl)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 36716-60-6
di-n-propylaminoethyl chloride

: 66203-89-2
N-(4,7-dimethoxy-6-hydroxy-5-benzofuranyl)-N'-methylurea

: 75902-75-9
1-[6-(2-Dipropylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: With potassium carbonate; In acetonitrile; for 4h; Heating;
DOI:10.1021/jm00134a007

Reference yield:

: 52631-79-5
N-(4,7-dimethoxy-6-hydroxy-5-benzofuranyl)acetamide

: 75902-75-9
1-[6-(2-Dipropylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / HCl / ethanol / 20 h / Heating

2: 89 percent / CHCl₃ / 2 h / Ambient temperature

3: 77 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With hydrogenchloride; potassium carbonate; In ethanol; chloroform; acetonitrile;
DOI:10.1021/jm00134a007

Reference yield:

: 484-51-5
5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran

: 75902-75-9
1-[6-(2-Dipropylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: Multi-step reaction with 5 steps

1: 82 percent / hydroxylamine hydrochloride, conc. NaOH / ethanol; H₂O / 6 h / Heating

2: 75 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C

3: 90 percent / HCl / ethanol / 20 h / Heating

4: 89 percent / CHCl₃ / 2 h / Ambient temperature

5: 77 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With hydrogenchloride; sodium hydroxide; hydroxylamine hydrochloride; potassium carbonate; acetic acid; In ethanol; chloroform; water; acetonitrile;
DOI:10.1021/jm00134a007